Feasibility of Fully Automated Hypnosis, Analgesia, and Fluid Management Using 2 Independent Closed-Loop Systems During Major Vascular Surgery: A Pilot Study

Feasibility of Fully Automated Hypnosis, Analgesia, and Fluid Management Using 2 Independent Closed-Loop Systems During Major Vascular Surgery: A Pilot Study
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DOI:
10.1213/ane.0000000000003433
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发表时间:
2019-06-01
影响因子:
5.7
通讯作者:
Barvais, Luc
Barvais, Luc
中科院分区:
医学2区
文献类型:
--
作者:
Joosten, Alexandre;Jame, Vincent;Barvais, Luc

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使用处理过的脑电图监测进行静脉麻醉和镇痛的自动滴定不再是一个新概念。用于提供目标导向的流体治疗的流体给药的闭环控制也已被越来越多地描述。然而,在接受大血管手术的患者中同时将2个独立的闭环系统组合在一起之前尚未详细说明。本初步研究的目的是在评价真实患者结局的大型研究中实施前,评价在接受大血管手术的患者中使用2个独立闭环控制器进行全自动催眠、镇痛和液体管理的临床性能。
Automated titration of intravenous anesthesia and analgesia using processed electroencephalography monitoring is no longer a novel concept. Closed-loop control of fluid administration to provide goal-directed fluid therapy has also been increasingly described. However, simultaneously combining 2 independent closed-loop systems together in patients undergoing major vascular surgery has not been previously detailed. The aim of this pilot study was to evaluate the clinical performance of fully automated hypnosis, analgesia, and fluid management using 2 independent closed-loop controllers in patients undergoing major vascular surgery before implementation within a larger study evaluating true patient outcomes.