Clinical Characteristics and Predictors of In-Hospital Mortality in Patients With Cardiogenic Shock
Clinical Characteristics and Predictors of In-Hospital Mortality in Patients With Cardiogenic Shock
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DOI：
10.1161/circheartfailure.120.008141
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发表时间：
2021-06-01
影响因子：
9.7
通讯作者：
Gwon, Hyeon-Cheol
中科院分区：
文献类型：
--
作者：
Yang, Jeong Hoon;Choi, Ki Hong;Gwon, Hyeon-Cheol
背景技术背景：在当前的机械循环支持时代，有限的数据是由各种疾病引起的心源性休克（CS）的预后。我们调查的特点和预测因素在韩国患者的住院死亡率CS. METHODS：RESCUE研究（回顾性和前瞻性观察性研究，调查临床结局和疗效的左心室辅助装置与韩国CS患者）是一个多中心，回顾性和前瞻性注册的患者，提出与CS。2014年1月至2018年12月期间，从韩国12家主要研究中心入组了1247例CS患者。结果：住院死亡率为33.6%。休克的主要原因为缺血性心脏病（80.7%）、扩张型心肌病（6.1%）、心肌炎（3.2%）和非缺血性室性心律失常（2.5%）。1081例患者（86.7%）使用了血管加压药。最常用的血管加压药是多巴胺（63.4%），其次是去甲肾上腺素（57.3%）。314例患者（25.2%）使用了主动脉内球囊反搏，496例患者（39.8%）使用了体外膜式氧合器。多因素分析中，年龄≥ 70岁（优势比[OR]，2.73 [95%CI，1.89 - 3.94]，P
BACKGROUND: In the current era of mechanical circulatory support, limited data are available on prognosis of cardiogenic shock (CS) caused by various diseases. We investigated the characteristics and predictors of in-hospital mortality in Korean patients with CS.METHODS: The RESCUE study (Retrospective and Prospective Observational Study to Investigate Clinical Outcomes and Efficacy of Left Ventricular Assist Device for Korean Patients With CS) is a multicenter, retrospective, and prospective registry of patients that presented with CS. Between January 2014 and December 2018, 1247 patients with CS were enrolled from 12 major centers in Korea. The primary outcome was in-hospital mortality.RESULTS: In-hospital mortality rate was 33.6%. The main causes of shock were ischemic heart disease (80.7%), dilated cardiomyopathy (6.1%), myocarditis (3.2%), and nonischemic ventricular arrhythmia (2.5%). Vasopressors were used in 1081 patients (86.7%). The most frequently used vasopressor was dopamine (63.4%) followed by norepinephrine (57.3%). An intraaortic balloon pump was used in 314 patients (25.2%) and extracorporeal membrane oxygenator in 496 patients (39.8%). In multivariable analysis, age >= 70years (odds ratio [OR], 2.73 [95% CI, 1.89-3.94], P