HIGHLY INFORMATIVE COMPOUND HAPLOTYPES FOR THE HUMAN Y-CHROMOSOME
HIGHLY INFORMATIVE COMPOUND HAPLOTYPES FOR THE HUMAN Y-CHROMOSOME
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DOI：
10.1093/hmg/3.1.115
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发表时间：
1994-01-01
影响因子：
3.5
通讯作者：
TYLERSMITH, C
中科院分区：
文献类型：
--
作者：
MATHIAS, N;BAYES, M;TYLERSMITH, C
一组多态性 DNA 序列已用于分析 91 条 Y 染色体组的变异性。一些序列（DYZ1 和 DYZ2）具有高度多态性，可以区分所有染色体。其他序列的多态性较低，用于为每条染色体构建单倍型并将染色体分配给组。对这些基因座的最好理解可以用来构建一棵树，显示 Y 染色体组之间的进化关系。一般来说，不同种族背景的Y染色体属于不同的群体。
A collection of polymorphic DNA sequences has been used to analyse the variability of a panel of 91 Y chromosomes. Some sequences (DYZ1 and DYZ2) were highly polymorphic and allowed all of the chromosomes to be distinguished. Other sequences were less polymorphic and were used to construct a haplotype for each chromosome and to assign chromosomes to groups. The best understood of these loci could be used to construct a tree showing the evolutionary relationships between the groups of Y chromosomes. In general, Y chromosomes from different ethnic backgrounds belong to different groups.