Endogenous hormones and the risk of hip and vertebral fractures among older women
Endogenous hormones and the risk of hip and vertebral fractures among older women
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DOI：
10.1056/nejm199809103391104
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发表时间：
1998-09-10
影响因子：
158.5
通讯作者：
Ettinger, B
中科院分区：
文献类型：
--
作者：
Cummings, SR;Browner, WS;Ettinger, B
研究背景与方法。绝经后妇女血清内源性性激素和维生素D浓度可能影响髋部和椎体骨折的风险。在一项针对65岁及以上女性的队列研究中，我们比较了133名随后发生髋部骨折的女性和138名随后发生椎体骨折的女性的基线血清激素浓度，并从同一队列中随机选择对照女性。服用雌激素的女性被排除在外。结果根据年龄和体重进行了调整。血清雌二醇浓度检测不到的妇女(
Background and Methods. In postmenopausal women, the serum concentrations of endogenous sex hormones and vitamin D might influence the risk of hip and vertebral fractures. In a study of a cohort of women 65 years of age or older, we compared the serum hormone concentrations at base line in 133 women who subsequently had hip fractures and 138 women who subsequently had vertebral fractures with those in randomly selected control women from the same cohort. Women who were taking estrogen were excluded. The results were adjusted for age and weight.Results. The women with undetectable serum estradiol concentrations (