Quality of life and symptom dimensions of patients with obsessive-compulsive disorder
Quality of life and symptom dimensions of patients with obsessive-compulsive disorder
复制标题
DOI：
10.1016/j.psychres.2009.04.005
复制
发表时间：
2010-09-30
影响因子：
11.3
通讯作者：
Versiani, Marcio
中科院分区：
文献类型：
--
作者：
Fontenelle, Isabela S.;Fontenelle, Leonardo F.;Versiani, Marcio
本研究的目的是评估强迫症状、共病焦虑抑郁症状和社会人口学特征的不同维度对强迫症（OCD）患者生活质量的影响。我们使用社会人口学调查问卷、《精神疾病诊断与统计手册》第四版 (DSM-IV) 的结构化临床访谈、简式健康调查 36 (SF-36)、储蓄量表修订版、强迫量表修订版、贝克抑郁量表对 53 名强迫症患者和来自社区的 53 名年龄和性别匹配的个体进行了评估和贝克焦虑量表。进行了一系列逐步线性回归分析，将 SF-36 维度作为因变量，将社会人口统计学和临床特征作为独立变量。除身体疼痛外，强迫症患者在 SF-36 测量的所有维度上都表现出明显较低的生活质量。一个包含抑郁症状、囤积和就业状况的模型预测了强迫症患者生活质量的社会功能维度的 62% 的方差。洗涤症状解释了 31% 由于身体健康问题而导致的限制差异。此外，一系列包含抑郁症状但不包含强迫症状的模型解释了 SF-36 的其余维度。因此，抑郁和焦虑症状的严重程度似乎是强迫症患者生活质量水平的有力决定因素。 (C) 2009 Elsevier Ireland Ltd. 保留所有权利。
The aim of this study was to evaluate the impact of different dimensions of obsessive-compulsive symptoms, of co-morbid anxious depressive symptoms, and of sociodemographic characteristics on the quality of life of patients with obsessive-compulsive disorder (OCD). We evaluated 53 patients with OCD and 53 age- and gender-matched individuals from the community with a sociodemographic questionnaire, the Structured Clinical Interview for the Diagnosis of Diagnostic and Statistical Manual of Mental Disorders, fourth Edition, (DSM-IV), the Short-Form Health Survey-36 (SF-36), the Saving Inventory-Revised, the Obsessive-Compulsive Inventory-Revised, the Beck Depression Inventory and the Beck Anxiety Inventory. A series of stepwise linear regression analyses were performed, having the SF-36 dimensions as the dependent variables and the sociodemographic and clinical features as the independent ones. Patients with OCD displayed significantly lower levels of quality of life in all dimensions measured by the SF-36, except bodily pain. A model that included depressive symptoms, hoarding and employment status predicted 62% of the variance of the social functioning dimension of the quality of life of patients with OCD. Washing symptoms explained 31% of the variance of limitation due to physical health problems. Further, a series of models that included depressive, but not obsessive-compulsive symptoms, explained the remaining SF-36 dimensions. The severity of depressive and anxiety symptoms seems, therefore, to be powerful determinants of the level of quality of life in patients with OCD. (C) 2009 Elsevier Ireland Ltd. All rights reserved.