Visceral leishmaniasis: Consequences of a neglected disease in a Bangladeshi community
Visceral leishmaniasis: Consequences of a neglected disease in a Bangladeshi community
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DOI：
10.4269/ajtmh.2003.69.624
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发表时间：
2003-12-01
影响因子：
3.3
通讯作者：
Maguire, JH
中科院分区：
文献类型：
--
作者：
Ahluwalia, IB;Bern, C;Maguire, JH
内脏利什曼病或黑热病影响农村穷人，造成严重的发病率和死亡率。我们研究了流行病学，社会和经济影响KA在孟加拉国的一个村庄。一项对2,348人进行的基于人口的调查显示，2000年至2002年，KA的发病率为每年2%，成年妇女的病死率为19%，而其他人口群体的病死率为6-8%。黑热病病例在地理上集中在该村的某些地区。抗利什曼病药物短缺以及诊断和治疗费用高昂给受影响家庭造成了巨大的情感和经济困难。社区希望更多地了解KA，并愿意采取集体行动来应对它造成的问题。为了减少流行地区的KA负担，社区的努力应该辅之以有效的治疗方案，以确保获得适当和负担得起的诊断和病例管理。
Visceral leishmaniasis, or kala azar (KA), affects the rural poor, causing significant morbidity and mortality. We examined the epidemiologic, social, and economic impact of KA in a village in Bangladesh. A population-based survey among 2,348 people demonstrated a KA incidence of 2% per year from 2000 to 2002, with a case-fatality rate of 19% among adult women, compared with 6-8% among other demographic groups. Kala azar cases were geographically clustered in certain sections of the village. Anti-leishmanial drug shortages and the high cost of diagnosis and treatment caused substantial emotional and economic hardship for affected families. Communities wanted to learn more about KA, and were willing to take collective action to confront the problems it causes. To decrease the KA burden in endemic areas, community efforts should be supplemented with effective treatment programs to ensure access to appropriate and affordable diagnosis and case management.