Chemospecific C3- and C2-Olefinations of Isatins by TfOH-Promoted Tandem Aldol-Grob and Semiacetalization-Grob Fragmentations

Chemospecific C3- and C2-Olefinations of Isatins by TfOH-Promoted Tandem Aldol-Grob and Semiacetalization-Grob Fragmentations
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DOI：
10.1021/acs.orglett.3c01475
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发表时间：
2023
期刊：
Organic Letters
影响因子：
--
通讯作者：
Yuefei Hu
Yuefei Hu
中科院分区：
--
文献类型：
--
作者：
Hongchen Li;Lidong Shan;Chulong Liu;Nan Liu;Xinyan Wang;Yuefei Hu

文献摘要

相似文献

A novel method for TfOH-promoted chemospecific C3- and C2-olefinations of isatins is developed, which offers the first examples of Grob fragmentation using isatins and amides as substrates.