EasyModeller: A graphical interface to MODELLER.
EasyModeller: A graphical interface to MODELLER.
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DOI：
10.1186/1756-0500-3-226
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发表时间：
2010-08-16
影响因子：
1.8
通讯作者：
Reddanna P
中科院分区：
文献类型：
--
作者：
Kuntal BK;Aparoy P;Reddanna P
MODELLER是一个自动蛋白质同源性建模程序。它是蛋白质三维结构同源或比较建模的最广泛使用的工具之一，但大多数用户发现从MODELLER开始有点困难，因为它是基于命令行的，需要基本的Python脚本知识才能有效地使用它。该研究的目的是开发“EasyModeller”工具作为前端图形界面MODELLER使用Perl/Tk，它可以作为一个独立的工具，在Windows平台上与MODELLER和Python预装。它可以帮助没有经验的用户以简单直接的方式进行蛋白质模型的建模，评估，可视化和优化。EasyModeler提供了一个图形化的直接界面和功能，作为一个独立的工具，可以在一个标准的个人电脑与Microsoft Windows作为操作系统使用。
MODELLER is a program for automated protein Homology Modeling. It is one of the most widely used tool for homology or comparative modeling of protein three-dimensional structures, but most users find it a bit difficult to start with MODELLER as it is command line based and requires knowledge of basic Python scripting to use it efficiently. The study was designed with an aim to develop of "EasyModeller" tool as a frontend graphical interface to MODELLER using Perl/Tk, which can be used as a standalone tool in windows platform with MODELLER and Python preinstalled. It helps inexperienced users to perform modeling, assessment, visualization, and optimization of protein models in a simple and straightforward way. EasyModeller provides a graphical straight forward interface and functions as a stand-alone tool which can be used in a standard personal computer with Microsoft Windows as the operating system.