Histopathology of drug eruptions - general criteria, common patterns, and differential diagnosis.
Histopathology of drug eruptions - general criteria, common patterns, and differential diagnosis.
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DOI：
10.5826/dpc.0101a09
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发表时间：
2011-01-31
影响因子：
2.8
通讯作者：
Metze D
中科院分区：
文献类型：
--
作者：
Weyers W;Metze D
药疹是最常见的皮肤炎性疾病之一，也是最常做活检的疾病之一。然而，药疹的组织病理学检查的价值经常存在争议。原因之一是药疹的组织病理学变化范围很广。然而，药疹的每一种组织病理学模式的鉴别诊断数量有限，并且有许多标准和线索可用于将药疹与与这些模式相关的其他疾病区分开来。通过识别常见的模式，考虑鉴别诊断，并注意不同的线索，药疹的组织病理学诊断通常可以有把握地做出。
Drug eruptions are among the most common inflammatory diseases of the skin and also among those biopsied most often. Yet, the value of histopathologic examination of drug eruptions has often been disputed. One reason is that the spectrum of histopathologic changes in drug eruptions is broad. Nevertheless, each histopathologic pattern assumed by drug eruptions has a limited number of differential diagnoses, and numerous criteria and clues are available to distinguish drug eruptions from other diseases associated with those patterns. By recognition of common patterns, consideration of differential diagnoses, and attention to distinct clues, a histopathologic diagnosis of drug eruption can usually be made with confidence.