Equating EORTC QLQ-C30 and FACT-G scores and its use in oncological research
Equating EORTC QLQ-C30 and FACT-G scores and its use in oncological research
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DOI：
10.1016/j.ejca.2006.08.016
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发表时间：
2006-12-01
影响因子：
8.4
通讯作者：
Kemmler, G.
中科院分区：
文献类型：
--
作者：
Holzner, B.;Bode, R. K.;Kemmler, G.
目的：基于相应的子量表，研究欧洲癌症研究和治疗组织核心问卷（EORTC QLQ-C30）和癌症治疗功能评估-一般（FACT-G）的等效性，并在适当时推导出将QLQ-C30评分转换为FACT-G评分的方案，反之亦然，用于肿瘤学。research.Method:使用了737例癌症患者（平均年龄51.4 ± 7.6（SD），63%为女性，25%为当前化疗患者）的校准样本，这些患者填写了两份生活质量（QOL）问卷。经典测验理论和Rasch测量模型都被应用。两种QOL工具共有的四个分量表中的三个（身体、情感、功能）被证明适合等同于（相应分量表物理（r = 0.77）、情感领域（r = 0.60）角色/功能（r = 0.63），相对于其内部一致性，合并分量表的充分单向性，与Rasch模型的拟合令人满意）。这些分量表的转换表generated.Conclusions：在这项研究中开发的转换表（身体，情感和功能/角色域）出现有前途的EORTC QLQ-C30和FACT-G评分的患者样本之间的比较。(c)2006爱思唯尔有限公司保留所有权利。
Objective: To investigate the equivalence of the European organization for Research and Treatment of Cancer Core Questionnaire (EORTC QLQ-C30) and the Functional Assessment for Cancer Therapy - General (FACT-G) on the basis of corresponding subscales, and where appropriate to derive a scheme for converting QLQ-C30 scores into FACT-G scores and vice versa for use in oncological. research.Method: A calibration sample of 737 cancer patients (mean age 51.4 +/- 7.6 (SD), 63% female, 25% with current chemotherapy) who filled in both quality of life (QOL) questionnaires was used. Both classical test theory and the Rasch measurement model were applied.Results: Three of the four subscales common to both QOL instruments (physical, emotional, functional) proved suitable for equating (acceptable inter-correlations of corresponding subscales physical (r = 0.77), emotional domain (r = 0.60) role/functional (r = 0.63) relative to their internal consistency, sufficient uniclimensionality of pooled subscales, satisfactory fit to the Rasch model). Conversion tables for these subscales were generated.Conclusions: The conversion tables developed in this study (physical, emotional and functional/role domain) appear promising for the comparison between EORTC QLQ-C30 and FACT-G scores of patient samples. (c) 2006 Elsevier Ltd. All rights reserved.