New animal model for studying mastication in oral motor disorders
New animal model for studying mastication in oral motor disorders
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DOI：
10.1177/154405910308200415
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发表时间：
2003-04-01
影响因子：
7.6
通讯作者：
Yoshida, N
中科院分区：
文献类型：
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作者：
Okayasu, I;Yamada, Y;Yoshida, N
为了确定小鼠口腔行为的基本参数，我们记录了自由行为小鼠进食不同质地食物时的三维下颌运动轨迹以及咬肌和二腹肌的活动。结果表明：(1)食物的摄取和咀嚼具有特征性的下颌运动模式；(2)咀嚼周期的模式可分为张开、闭合和突出(力量)三种；(3)食物质地影响着颌骨运动、肌肉活动和咀嚼节律的基本模式。小鼠的口腔运动行为似乎与其他实验动物相同，因此小鼠是研究咀嚼运动的合适动物模型。
To identify the basic parameters of oral behavior in mice, we recorded the three-dimensional jaw movement trajectories and masseter and digastric muscle activities in freely behaving mice eating foods of various textures. Results showed that: (1) there are characteristic jaw movement patterns for food intake and mastication; (2) the pattern in a chewing cycle may be divided into opening, closing, and protruding (power) strokes; and (3) food texture affects basic patterns of jaw movement, muscle activities, and chewing rhythms. The oral motor behavior of mice appears identical to those of other experimental animals, so mice are appropriate animal models for the study of mastication.