PREVALENCE OF NONTUBERCULOUS MYCOBACTERIA IN WATER-SUPPLIES OF HEMODIALYSIS CENTERS
PREVALENCE OF NONTUBERCULOUS MYCOBACTERIA IN WATER-SUPPLIES OF HEMODIALYSIS CENTERS
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DOI：
10.1128/aem.54.12.3122-3125.1988
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发表时间：
1988-12-01
影响因子：
4.4
通讯作者：
GOOD, RC
中科院分区：
文献类型：
--
作者：
CARSON, LA;BLAND, LA;GOOD, RC
血液透析患者的非结核分枝杆菌（NTM）感染与血液透析器再处理用水有关。这项研究的目的是确定从美国115个随机选择的透析中心收集的13周内的水样中NTM和其他细菌的患病率。通过膜过滤器测定确定总活菌计数;通过在过滤前用1%甲醛（HCHO）给药各水样的一部分，获得NTM的回收率增加。NTM在透析中心的供水中分布广泛，发生频率较高。在95个中心（83%）的水中检测到NTM，50%的检测样本含有NTM。本研究的结果支持使用4% HCHO或化学杀菌等效物对重复使用的透析器进行消毒的建议。
Infection of hemodialysis patients with nontuberculous mycobacteria (NTM) has been associated with water used in reprocessing hemodialyzers. This study was conducted to determine the prevalence of NTM and other bacteria in water samples collected over a 13-week period from 115 randomly selected dialysis centers in the United States. Total viable counts were determined by membrane filter assays; increased recovery of NTM was obtained by dosing a portion of each water sample with 1% formaldehyde (HCHO) before filtering. NTM were widely distributed and occurred with a frequency in water supplies in dialysis centers. NTM were detected in water from 95 centers (83%), and 50% of all samples examined contained NTM. The results of this study support recommendations to use 4% HCHO or a chemical germicidal equivalent for disinfecting dialyzers that are to be reused.