Concordance between timeline follow-back and single-question assessment of self-reported smoking in a clinical trial
Concordance between timeline follow-back and single-question assessment of self-reported smoking in a clinical trial
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DOI：
10.1080/08897077.2016.1154494
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发表时间：
2016-01-01
期刊：
影响因子：
3.5
通讯作者：
Toll, Benjamin
中科院分区：
文献类型：
--
作者：
Bernstein, Steven L.;Rosner, June;Toll, Benjamin
背景：戒烟临床试验使用自我报告和生物标志物评估戒烟。每种方法的最佳方法尚不清楚;一个常见的问题是评估前7天的吸烟情况。相反，时间轴追踪（TLFB）是另一种经常用于评估治疗试验中酒精使用的技术;它在戒烟研究中使用频率较低。本研究的目的是评估7天吸烟问题和7天TLFB之间的一致性。研究方法：对2010年10月至2012年12月在忙碌的城市医院急诊科（艾德）进行的戒烟随机临床试验数据进行了次要分析。在1、3和12个月时，通过电话联系受试者以评估吸烟状况。那些在3个月后报告禁欲的人被要求返回现场测量呼出的一氧化碳。对于该分析，比较了受试者在1个月时的吸烟状态，回答了同时提出的2个问题，解决了7天时点烟草使用率和7天TLFB。结果：780例受试者中，666例（85.4%）可接受1个月随访。其中，99名（14.9%）在回答7天问题时报告不吸烟，96名（14.4%）在回答7天TLFB时报告不吸烟。两种方法之间的总体比例一致率为98.6%，kappa为0.95（95%置信区间[CI]：0.91-0.98）。结论：一个单一的问题，评估吸烟在7天提供了良好的一致性与更详细的TLFB。这一问题似乎足以评估戒烟临床试验中自我报告的烟草使用情况。
Background: Smoking cessation clinical trials assess tobacco abstinence using self-report and biomarkers. Optimum methods for each are unclear; a common question assesses smoking in the prior 7days. In contrast, timeline follow-back (TLFB) is another technique often used to assess use of alcohol in treatment trials; it is used less frequently in studies of smoking cessation. The goal of this study was to assess concordance between the 7-day smoking question and a 7-day TLFB. Methods: Secondary analysis of data from a randomized clinical trial of smoking cessation was conducted at a busy, urban hospital emergency department (ED) from October 2010 to December 2012. At 1, 3, and 12months, subjects were contacted by phone to assess smoking status. Those reporting abstinence at 3months were asked to return for an in-person measurement of exhaled carbon monoxide. For this analysis, smoking status at 1month was compared for subjects in response to 2 questions asked concurrently, addressing 7-day point prevalence tobacco use and a 7-day TLFB. Results: Of 780 subjects, 666 (85.4%) were available for 1-month follow-up. Of these, 99 (14.9%) reported no smoking in response to the 7-day question, and 96 (14.4%) reported no smoking in response to the 7-day TLFB. The overall proportionate agreement between the 2 methods was 98.6%, with a kappa of 0.95 (95% confidence interval [CI]: 0.91-0.98). Conclusions: A single question that assesses smoking at 7days provides excellent concordance with the more detailed TLFB. The single question appears adequate to assess self-reported tobacco use in clinical trials of smoking cessation.