Experimental study on bioluminescence tomography with multimodality fusion.
Experimental study on bioluminescence tomography with multimodality fusion.
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DOI：
10.1155/2007/86741
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发表时间：
2007
影响因子：
7.6
通讯作者：
Wang G
中科院分区：
文献类型：
--
作者：
Lv Y;Tian J;Cong W;Wang G
为了验证先验信息对生物发光断层扫描（BLT）非唯一性问题的影响，通过多视图非接触检测模式进行基于多模态成像融合的BLT实验，该实验结合了microCT扫描仪获得的解剖信息和基于漫反射测量的背景光学特性。在重建过程中，利用自适应有限元方法（FEM）和先验允许源区域细化重建结果并提高数值鲁棒性和效率。先验信息的缺失和使用之间的比较表明，多模态成像融合对于定量 BLT 重建至关重要。
To verify the influence of a priori information on the nonuniqueness problem of bioluminescence tomography (BLT), the multimodality imaging fusion based BLT experiment is performed by multiview noncontact detection mode, which incorporates the anatomical information obtained by the microCT scanner and the background optical properties based on diffuse reflectance measurements. In the reconstruction procedure, the utilization of adaptive finite element methods (FEMs) and a priori permissible source region refines the reconstructed results and improves numerical robustness and efficiency. The comparison between the absence and employment of a priori information shows that multimodality imaging fusion is essential to quantitative BLT reconstruction.