The regulatory roles and potential prognosis implications of long non-coding RNAs in gastric cancer.
The regulatory roles and potential prognosis implications of long non-coding RNAs in gastric cancer.
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DOI：
10.14670/hh-18-188
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发表时间：
2020
期刊：
影响因子：
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通讯作者：
Qing Yang
中科院分区：
文献类型：
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作者：
Yue Wang;Fan Yang;Qing Yang
Accumulating dysregulated lncRNAs have been demonstrated to execute vital functions in the pathogenesis and progress of gastric cancer (GC) through versatile molecular mechanisms. In this review, we classify the mechanisms of dysregulated lncRNAs in GC into several governing types according to their roles at molecular level. For each regulatory role, we illustrate several instructive examples and introduce significant effects of lncRNAs on cellular biological properties of GC. Besides, we summarize a group of lncRNA-signatures that are potential biomarkers in the prediction of prognosis for GC patients.
