The Discovery-Oriented Approach to Organic Chemistry. 5. Stereochemistry of E2 Elimination: Elimination of cis- and trans-2-Methylcyclohexyl Tosylate
The Discovery-Oriented Approach to Organic Chemistry. 5. Stereochemistry of E2 Elimination: Elimination of cis- and trans-2-Methylcyclohexyl Tosylate
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以发现为导向的有机化学方法。
DOI：
10.1021/ed078p79
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发表时间：
2001
影响因子：
3
通讯作者：
R. Mohan
中科院分区：
文献类型：
--
作者：
Marcus E. Cabay;Brad J. Ettlie;Adam J. Tuite;K. Welday;R. Mohan
E2 消除是有机化学中最重要的反应之一，在大二有机课程中进行了相当详细的讨论。我们开发了一个以发现为导向的实验室，用于说明 E2 消除反应的立体化学，并且是 1H NMR 光谱学的一个很好的练习。增加的发现元素确保保留学生的兴趣和热情。
The E2 elimination is one of the most important reactions in organic chemistry and is discussed in considerable detail in a sophomore organic course. We have developed a discovery-oriented lab that illustrates the stereochemistry of the E2 elimination reaction and is a good exercise in 1H NMR spectroscopy. The added element of discovery insures that student interest and enthusiasm are retained.