Semifluorinated Synergistic Nonfouling/Fouling-Release Surface
Semifluorinated Synergistic Nonfouling/Fouling-Release Surface
复制标题
半氟化协同防污/防污表面
DOI：
10.1021/acsami.7b03258
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发表时间：
2017
影响因子：
9.5
通讯作者：
Huang Xiaoyu
中科院分区：
文献类型：
--
作者：
Xu Binbin;Liu Yajing;Sun Xiaowen;Hu Jianhua;Shi Ping;Huang Xiaoyu
采用聚乙二醇（PEO）和聚甲基丙烯酸2，2，2-三氟乙酯（PFMA）侧链沿聚合物主链沿着密集分布在同一重复单元上的ab-PFMA-PEO不对称分子刷，制备了一种含氟协同防垢/除垢表面。以溴丙烯酸酯-炔三官能度单体通过可逆加成-断裂链转移均聚反应制备的含炔基和2-溴丙酸酯两个官能团的聚（溴丙烯酸酯-炔）大分子试剂为基础，通过同步原子转移自由基聚合和Cu催化的叠氮/炔环加成“点击”反应，在一步法体系中合成了b-PFMA-PEO不对称分子刷. b-PFMA-PEO不对称分子刷的旋转浇铸薄膜表现出协同的防污性能，其中PEO侧链赋予表面防污特性，而PFMA侧链由于它们的低表面能而显示防污释放功能。蛋白质吸附和细胞粘附测试提供了估计的不对称分子刷表面，这被证明是由主链的聚合度和长度的PEO和PFMA侧链的聚合度的影响。由于组成的不均匀性，所有不对称分子刷表面都显示出相当大的粘附性能，与裸露表面相比，蛋白质吸附（至少45%，高达75%）和细胞粘附（至少70%，高达90%）少得多。
The preparation of a fluorine-containing synergistic nonfouling/fouling-release surface, using ab-PFMA–PEO asymmetric molecular brush possessing both poly(ethylene glycol) (PEO) and poly(2,2,2-trifluoroethyl methacrylate) (PFMA) side chains densely distributed on the same repeat unit along the polymeric backbone, is reported. On the basis of the poly(Br-acrylate-alkyne) macroagent comprising two functionalities (alkynyl and 2-bromopropionate), which is prepared by reversible addition–fragmentation chain transfer homopolymerization of a new trifunctional acrylate monomer of Br-acrylate-alkyne,b-PFMA–PEO asymmetric molecular brushes are obtained by concurrent atom transfer radical polymerization and Cu-catalyzed azide/alkyne cycloaddition “click” reaction in a one-shot system. A spin-cast thin film of theb-PFMA–PEO asymmetric molecular brush exhibits a synergistic antifouling property, in which PEO side chains endow the surface with a nonfouling characteristic, whereas PFMA side chains display the fouling-release functionality because of their low surface energy. Both protein adsorption and cell adhesion tests provided estimates of the antifouling activity of the asymmetric molecular brush surfaces, which was demonstrated to be influenced by the degree of polymerization of the backbone and the length of the PEO and PFMA side chains. With compositional heterogeneities, all asymmetric molecular brush surfaces show considerable antifouling performance with much less protein adsorption (at least 45% off, up to 75% off) and cell adhesion (at least 70% off, up to 90% off) in comparison with a bare surface.