Mechanically strong poly (vinyl alcohol) hydrogel with macropores and high porosity
Mechanically strong poly (vinyl alcohol) hydrogel with macropores and high porosity
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DOI：
10.1016/j.matlet.2020.127504
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发表时间：
2020-05
影响因子：
3
通讯作者：
Heng Li;Cheng-wei Wu;Sen Wang;Wei Zhang
中科院分区：
文献类型：
--
作者：
Heng Li;Cheng-wei Wu;Sen Wang;Wei Zhang
以琼脂糖（AG）为致孔剂，制备了大孔、高孔隙率、机械强度高的聚乙烯醇（PVA）水凝胶。AG不仅通过促进冰粒的成核和生长而引发大孔的形成，而且通过增加PVA的结晶度和分子间氢键而增强力学性能。体外细胞实验表明，所制备的PVA水凝胶具有细胞相容性，软骨细胞可以在大孔内增殖。
The macroporous, high porosity and mechanically strong poly (vinyl alcohol) (PVA) hydrogels were developed using agarose (AG) as the pore inducing agent. The AG not only incurs the formation of macropores by promoting the nucleation and growth of ice particles, but also strengthens the mechanical properties by increasing the crystallinity of PVA and the inter-molecular hydrogen bonds. Thein vitrocell experiments imply that the obtained PVA hydrogels is cytocompatible and the chondrocytes can proliferate in the macropores.