EFFECTS OF CARBOHYDRATE INGESTION ON ACUTE LEUKOCYTE, CORTISOL, AND INTERLEUKIN-6 RESPONSE IN HIGH-INTENSITY LONG-DISTANCE RUNNING
EFFECTS OF CARBOHYDRATE INGESTION ON ACUTE LEUKOCYTE, CORTISOL, AND INTERLEUKIN-6 RESPONSE IN HIGH-INTENSITY LONG-DISTANCE RUNNING
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DOI：
10.1519/jsc.0000000000000470
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发表时间：
2014-10-01
影响因子：
3.2
通讯作者：
Mero, Antti A.
中科院分区：
文献类型：
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作者：
Ihalainen, Johanna K.;Vuorimaa, Timo;Mero, Antti A.
Ihalainen， JK, Vuorimaa， T, Puurtinen， R, Hamalainen， I和Mero， AA。高强度长跑中碳水化合物摄入对急性白细胞、皮质醇和白细胞介素-6反应的影响。[J]中国体育杂志，28(10):2786-2792,2014 .本研究旨在探讨摄入不同碳水化合物浓度（0、1.5和7%）的液体对高强度长跑后急性免疫应激反应的影响。在随机、双盲、安慰剂（PLA）对照设计中，以75%的最大摄氧量进行连续18至20公里的跑步，同时补充碳水化合物（CHO7%， 7%碳水化合物溶液）和低碳水化合物（低cho1.5%， 1.5%碳水化合物溶液）。7名业余选手（4男3女）完成了全部3项试验。在基线（PRE）和跑步后（POST）立即采集血液。在每个试验中，跑步任务诱导白细胞（白细胞）、中性粒细胞和白细胞介素-6 （IL-6）计数显著增加（p 0.05）。PLA和低cho1.5%组皮质醇升高显著（p 0.05），而CHO7%组无显著升高。与PLA相比，CHO7%显著降低了总白细胞和中性粒细胞浓度的升高（p 0.05）。运动后IL-6水平与基线比较均显著升高（p < 0.05）。白细胞介素-6 （IL-6）浓度在试验间无显著差异。低碳水化合物1.5%运动饮料与PLA在测量变量上没有显著差异，这表明低碳水化合物运动饮料的碳水化合物摄取量和摄取率（15 g, 10 gh(-1)）不足以显著保护高强度长跑引起的应激，而摄入CHO7% （45 gh(-1)）则减弱了显著的皮质醇反应，并显著降低了白细胞反应。
Ihalainen, JK, Vuorimaa, T, Puurtinen, R, Hamalainen, I and Mero, AA. Effects of carbohydrate ingestion on acute leukocyte, cortisol, and interleukin-6 response in high-intensity long-distance running. J Strength Cond Res 28(10): 2786-2792, 2014The purpose of this study was to investigate the effect of ingestion of fluids with different carbohydrate concentrations (0, 1.5, and 7%) on the acute immune stress responses after high-intensity long-distance running. Continuous 18- to 20-km run was performed at 75% of maximal oxygen uptake with carbohydrate supplementation (CHO7%, 7% carbohydrate solution) and low-carbohydrate supplementation (lowCHO1.5%, 1.5% carbohydrate solution) in a randomized, double-blind, placebo (PLA) controlled design. Seven recreational runners (4 men and 3 women) completed all 3 trials. Blood was collected at baseline (PRE) and immediately after the run (POST). The running task induced significant (p 0.05) increases in leukocyte (white blood cells), neutrophil, and interleukin-6 (IL-6) counts in every trial. There was a significant (p 0.05) increase in cortisol with PLA and lowCHO1.5% but not with CHO7%. Increase in total leukocyte and neutrophil concentration was significantly lower with CHO7% compared with PLA (p 0.05). Postexercise IL-6 levels were significantly elevated when compared with baseline in all conditions (p 0.05). Interleukin-6 (IL-6) concentrations did not differ significantly between trials. LowCHO1.5% sport drink did not significantly differ from PLA in measured variables, which indicated that the amount and rate of carbohydrate ingestion (15 g, 10 gh(-1)) in low-carbohydrate sport drink was not enough to significantly protect from the stress induced by high-intensity long-distance running, whereas the ingestion of CHO7% (45 gh(-1)) blunted the significant cortisol response and significantly decreased the leukocyte response.