A library of IR bands of nucleic acids in solution
A library of IR bands of nucleic acids in solution
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DOI：
10.1016/s0301-4622(03)00035-8
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发表时间：
2003-06-01
影响因子：
3.8
通讯作者：
Gräslund, A
中科院分区：
文献类型：
--
作者：
Banyay, M;Sarkar, M;Gräslund, A
本文综述了各种构象的核酸的红外（IR）谱带特征的汇编和讨论。水溶液中DNA/RNA相关的整个光谱范围1800-800 cm（-1）被细分为四个部分。每一节包含对核酸结构的组特异性部分出现的条带的描述，如核碱基、基糖、糖磷酸和糖部分。该方法允许从一个光谱区域获得的信息与另一个进行比较。IR谱带库应便于从IR光谱详细和明确地分配核酸中的结构变化、配体结合等。第2节旨在突出对于核酸结构中的主要变化有用的特定特征。第2节还涉及一些最近的结果，其中红外光谱法已用于获得有关寡核苷酸中糖皱褶共存模式的半定量信息。(C)2003 Elsevier Science B. V.保留所有权利。
This review presents a compilation and discussion of infrared (IR) bands characteristic of nucleic acids in various conformations. The entire spectral range 1800-800 cm(-1) relevant for DNA/RNA in aqueous solution has been subdivided into four sections. Each section contains descriptions of bands appearing from group specific parts of nucleic acid structure, such as nucleobase, base-sugar, sugar-phosphate and sugar moiety. The approach allows comparisons of information obtained from one spectral region with another. The IR band library should facilitate detailed and unambiguous assignment of structural changes, ligand binding, etc. in nucleic acids from IR spectra. Section 2 is aimed at highlighting specific features that are useful for following major changes in nucleic acid structures. Section 2 also concerns some recent results, where IR spectroscopy has been used to obtain semi-quantitative information on coexisting modes of sugar pucker in oligonucleotides. (C) 2003 Elsevier Science B.V. All rights reserved.