Thromboembolic Events With Recombinant Activated Factor VII in Spontaneous Intracerebral Hemorrhage Results From the Factor Seven for Acute Hemorrhagic Stroke (FAST) Trial
Thromboembolic Events With Recombinant Activated Factor VII in Spontaneous Intracerebral Hemorrhage Results From the Factor Seven for Acute Hemorrhagic Stroke (FAST) Trial
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DOI：
10.1161/strokeaha.109.561712
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发表时间：
2010-01-01
期刊：
影响因子：
8.3
通讯作者：
Broderick, Joseph P.
中科院分区：
文献类型：
--
作者：
Diringer, Michael N.;Skolnick, Brett E.;Broderick, Joseph P.
背景和目的：由于高龄、高血压、动脉粥样硬化、糖尿病和不活动，脑出血患者发生血栓栓塞事件（TEs）的风险较高。使用重组活化因子VII （rFVIIa）可增加高危患者的TEs。我们回顾了急性出血性卒中因子7 （FAST）试验数据，以确定rFVIIa合并TE的频率和危险因素。方法：841例患者
Background and Purpose-Patients with intracerebral hemorrhage have a high risk of thromboembolic events (TEs) due to advanced age, hypertension, atherosclerosis, diabetes, and immobility. Use of recombinant activated factor VII (rFVIIa) could increase TEs in high-risk patients. Factor Seven for Acute Hemorrhagic Stroke (FAST) trial data were reviewed to define the frequency of and risk factors for TE with rFVIIa.Methods-Eight hundred forty-one patients presenting