Acute necrotizing encephalopathy in a child with H1N1 influenza infection
Acute necrotizing encephalopathy in a child with H1N1 influenza infection
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DOI：
10.1007/s00247-009-1487-z
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发表时间：
2010-02-01
影响因子：
2.3
通讯作者：
Deline, Carol
中科院分区：
文献类型：
--
作者：
Lyon, Jane B.;Remigio, Cheryl;Deline, Carol
自世界卫生组织于2009年6月宣布新型甲型H1N1流感为全球大流行以来，这一流感毒株的病例数持续上升。虽然大多数病例是轻度的，完全和顺利恢复，但已报告了多例严重感染并发症，包括死亡。据我们所知，美国的大多数致死性结局与肺部并发症有关。我们报告一个12岁的女孩感染甲型H1N1流感，其临床过程是复杂的快速进行性神经功能恶化和惊人的CT和MRI结果符合急性坏死性脑病（ANE）。据我们所知，这在儿科放射学文献中尚未报道。我们希望这个病例能提醒放射科医师注意这种并发症，并使放射科医师熟悉预示ANE的影像学表现。
Since the World Health Organization declared a global pandemic of novel influenza A H1N1 in June 2009, there has been a sustained rise in the number of cases of this strain of influenza. Although most cases are mild with complete and uneventful recovery, multiple cases of severe infection with complications including death have been reported. To the best of our knowledge, the majority of fatal outcomes in the United States have been related to pulmonary complications. We report a 12-year-old girl infected with influenza A H1N1 whose clinical course was complicated by rapid progressive neurologic deterioration and striking CT and MRI findings consistent with acute necrotizing encephalopathy (ANE). To our knowledge this has not been reported in the pediatric radiology literature. We hope this case will alert radiologists to this complication and familiarize radiologists with imaging findings that herald ANE.