Wall thickening pattern in atherosclerotic basilar artery stenosis
Wall thickening pattern in atherosclerotic basilar artery stenosis
复制标题
动脉粥样硬化性基底动脉狭窄的管壁增厚模式
DOI：
10.1007/s10072-015-2404-x
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发表时间：
2016-02-01
影响因子：
3.3
通讯作者：
Liu, Zunjing
中科院分区：
文献类型：
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作者：
Zhu, Xianjin;Liu, Lei;Liu, Zunjing
我们的目的是利用三维体积各向同性涡轮自旋回波采集（3D VISTA）研究动脉粥样硬化性基底动脉狭窄的壁增厚（WT）模式及其与临床特征的关系。前瞻性纳入了连续20例动脉粥样硬化性基底动脉狭窄患者。评估所有基底动脉VISTA图像的横截面切片，并将其分为偏心型和同心型。比较不同壁型WT患者的临床特征和狭窄程度。20例患者基底动脉横切面568片发现壁异常，其中偏心WT 497片（87.5%），同心WT 71片（12.5%）。20例患者中有11例（293片）全部呈偏心性WT， 9例（275片）同时呈偏心性WT（204片，74.2%）和同心性WT（71片，25.8%）。在最大管腔狭窄部位的切面上，只有1例患者出现同心WT。混合型WT（偏心和同心）患者比仅偏心WT患者更容易出现症状性狭窄（100比54.5%,p= 0.038）。动脉粥样硬化性基底动脉狭窄可以显示偏心和同心的小波变换。同心型WT在近一半的患者中发现，但往往位于最小的切片。没有病变是完全同心的。混合WT（同心和偏心）可能代表晚期动脉粥样硬化，伴有缺血性事件的高风险。
Our aim was to investigate wall thickening (WT) pattern of atherosclerotic basilar artery stenosis with three-dimensional volumetric isotropic turbo spin echo acquisition (3D VISTA), and the relationship with clinical characteristics. Twenty consecutive patients with atherosclerotic basilar artery stenosis were prospectively enrolled. All cross-sectional slices on VISTA images of basilar arteries were assessed, and classified as eccentric or concentric WT. Clinical characteristics and degree of stenosis were compared between the patients with different wall WT pattern. Wall abnormalities were identified in 568 cross-sectional slices in basilar arteries of 20 patients including eccentric WT in 497 (87.5 %) slices, and concentric WT in 71 (12.5 %) slices. In 11 of 20 patients, all the cross-sectional slices (293 slices) showed eccentric WT. In 9 of 20 patients, the cross-sectional slices (275 slices) showed both eccentric WT (204 slices, 74.2 %) and concentric WT (71 slices, 25.8 %). No lesion showed only concentric WT. At the slices of maximum luminal narrowing sites, only one patient showed concentric WT. Symptomatic stenosis was more common in the patients with mixed WT (eccentric and concentric), compared to patients with only eccentric WT (100 vs 54.5 %,p= 0.038). Atherosclerotic basilar artery stenosis could show both eccentric and concentric WT based on each slice analysis. Concentric WT was found in near half of the patients, but tended to locate in minimal slices. No lesion was entirely concentric. Lesions with mixed WT (concentric and eccentric) might represent advanced atherosclerosis with high risk of ischemic event.