WHEN DOES RHEUMATOID DISEASE START
WHEN DOES RHEUMATOID DISEASE START
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DOI：
10.1002/art.1780280503
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发表时间：
1985-01-01
影响因子：
--
通讯作者：
SALONEN, JT
中科院分区：
文献类型：
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作者：
AHO, K;PALOSUO, T;SALONEN, JT
从30名后来发展为血清阳性类风湿性关节炎的受试者中收集了与社区流行病学研究相关的储存血清标本。在这些类风湿前样本中的9个中，Rose-Waaler试验结果为阳性，在16个中，胶乳固定试验为阳性;当采集血液样本和疾病发作之间的间隔< 4年时，2/3的样本为阳性;当间隔≥ 4年时，1/3的样本为阳性。4年类风湿因子的出现先于临床疾病的发作，男性比女性更常见。
Stored serum specimens collected in connection with a community-oriented epidemiologic study were available from 30 subjects who later developed seropositive rheumatoid arthritis. In 9 of these pre-rheumatoid specimens, the Rose-Waaler test result was positive and in 16, the latex fixation test was positive; 2/3 of the samples were positive when the interval between taking the blood specimen and onset of the disease was < 4 yr; and 1/3 were positive when the interval was .gtoreq. 4 yr. The occurrence of rheumatoid factor preceded the onset of clinical disease more often in males than in females.