Intracerebral pain processing in a Yoga Master who claims not to feel pain during meditation
Intracerebral pain processing in a Yoga Master who claims not to feel pain during meditation
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DOI：
10.1016/j.ejpain.2004.12.006
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发表时间：
2005-10-01
影响因子：
3.6
通讯作者：
Kawakami, M
中科院分区：
文献类型：
--
作者：
Kakigi, R;Nakata, H;Kawakami, M
我们对一位声称在冥想时不会感到疼痛的瑜伽大师进行有害激光刺激后记录了脑磁图 (MEG) 和功能性磁共振成像 (fMRI)。至于背景 MEG 活动，与非冥想状态相比，冥想期间枕叶、顶叶和颞区的 α 频段峰值在 10 Hz 左右的功率大大增加，这可能意味着受试者在冥想期间非常放松，尽管他没有睡着。在冥想期间，MEG 从初级（SI）和次级体感皮质（SII）记录的初级疼痛相关皮质活动非常弱或缺失。至于功能磁共振成像记录，冥想和非冥想之间丘脑、SII-岛（主要是岛叶）和扣带皮层的活动水平存在显着变化。在非冥想期间，所有三个区域的活动均有所增加，与正常受试者的结果相似。相比之下，冥想期间所有三个区域的活动均较弱，并且水平低于丘脑的基线。最近的神经影像学和电生理学研究表明，疼痛感知的情绪方面主要涉及岛叶和扣带皮层。虽然我们无法清楚地解释瑜伽大师的这种异常情况，但与疼痛感知相关的多个区域的变化可能是造成这种情况的原因，因为疼痛是一种复杂的感觉和情感体验。 (c) 2004 年国际疼痛研究协会欧洲分会联合会。由爱思唯尔有限公司出版。保留所有权利。
We recorded magnetoencephalography (MEG) and functional magnetic resonance imaging (fMRI) following noxious laser stimulation in a Yoga Master who claims not to feel pain when meditating. As for background MEG activity, the power of alpha frequency bands peaking at around 10 Hz was much increased during meditation over occipital, parietal and temporal regions, when compared with the non-meditative state, which might mean the subject was very relaxed, though he did not fall asleep, during meditation. Primary pain-related cortical activities recorded from primary (SI) and secondary somatosensory cortices (SII) by MEG were very weak or absent during meditation. As for fMRI recording, there were remarkable changes in levels of activity in the thalamus, SII-insula (mainly the insula) and cingulate cortex between meditation and non-meditation. Activities in all three regions were increased during non-meditation, similar to results in normal subjects. In contrast, activities in all three regions were weaker during meditation, and the level was lower than the baseline in the thalamus. Recent neuroirnaging and electrophysiological studies have clarified that the emotional aspect of pain perception mainly involves the insula and cingulate cortex. Though we cannot clearly explain this unusual condition in the Yoga Master, a change of multiple regions relating to pain perception could be responsible, since pain is a complex sensory and emotional experience. (c) 2004 European Federation of Chapters of the International Association for the Study of Pain. Published by Elsevier Ltd. All rights reserved.