Elastography to assess the stage of liver fibrosis in children: Concepts, opportunities, and challenges.

Elastography to assess the stage of liver fibrosis in children: Concepts, opportunities, and challenges.
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DOI:
10.1002/cld.607
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发表时间:
2017-01-01
影响因子:
--
通讯作者:
Sirlin, Claude B
Sirlin, Claude B
中科院分区:
其他
文献类型:
--
作者:
Serai, Suraj D;Trout, Andrew T;Sirlin, Claude B

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弹性成像包括通过施加外力无创地估计组织弹性和相关机械特性的成像技术。弹性反映了组织在施加的应力下变形和恢复其正常形状的能力,并且与组织刚度有关。组织硬度反过来反映了组织的组成和结构。在肝脏中,组织硬度已被证明随着晚期纤维化而升高,并且与纤维化的阶段相关。 1
Elastography encompasses imaging techniques that noninvasively estimate tissue elasticity and related mechanical properties through the application of external forces. Elasticity reflects the ability of tissue to deform and resume its normal shape under an applied stress and relates to tissue stiffness. Tissue stiffness in turn reflects tissue composition and structure. In the liver, tissue stiffness has been shown to be elevated with advanced fibrosis and to correlate with the stage of fibrosis. 1