Exploring pralidoxime chloride as a universal electrochemical probe for organophosphorus pesticides detection
Exploring pralidoxime chloride as a universal electrochemical probe for organophosphorus pesticides detection
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探索氯化解磷定作为有机磷农药检测的通用电化学探针
DOI：
10.1016/j.aca.2017.06.006
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发表时间：
2017
影响因子：
6.2
通讯作者：
Ying Yibin
中科院分区：
文献类型：
--
作者：
Zheng Qiqi;Chen Yuan;Fan Kai;Wu Jian;Ying Yibin
报道了以氯解磷定(PAM-Cl)为通用电化学探针的非酶抑制电化学法测定有机磷农药(OPPS)。用循环伏安法表征了磷定和有机磷农药的氧化还原性能。采用差示脉冲伏安法(DPV)分析阴离子(氯离子和碘离子)的影响，优化测试条件，探讨磷定与有机磷农药的关系。结果表明，碘离子在解磷定的峰附近产生一个阳极峰，干扰有机磷农药的测定。用DPV测定PAM-Cl时，选择了峰电流大、峰电位低的磷酸盐缓冲溶液(pH 7.0)。毒死蜱、敌硫磷和甲基对硫磷是现有的三种有机磷农药检测方法的例子。PAM-Cl的峰电流随溶液中有机磷农药浓度的增加而减小。检出限分别为0.018μM、0.100μM和0.215μM。首次将PAM-Cl作为一种通用的电化学探针，建立了一种简便、廉价、稳定的检测有机磷农药的方法。
An electrochemical method based on non-enzymatic inhibition for the determination of organophosphorus pesticide (OPPs) using pralidoxime chloride (PAM-Cl) as a universal electrochemical probe was reported. Cyclic voltammetry was performed to characterize the redox properties of pralidoxime and OPPs. Differential pulse voltammetry (DPV) was carried out to analyze the influence of anion (chloride and iodide ions), to optimize the pH of testing condition, and to explore the relationship between pralidoxime and OPPs. The results showed that iodide ion generated an anodic peak close to the peak of pralidoxime, which would interfere in the detection of OPPs. Phosphate buffer solution (pH 7.0) was chosen because of its high peak current and low peak potential when testing PAM-Cl by DPV. Chlorpyrifos, fenthion, and methyl parathion were examples of three existing OPPs detection methods. The peak current of PAM-Cl decreased along with the increase of concentration of OPPs in the solution. The limit of detection was 0.018 μM, 0.100 μM, and 0.215 μM, respectively. It was the first time for PAM-Cl to be used as a universal electrochemical probe to develop a simple, cheap and stable method for OPPs detection.