Connecting the developing preterm brain

Connecting the developing preterm brain
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DOI:
10.1016/j.earlhumdev.2008.09.004
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发表时间:
2008-12-01
影响因子:
2.5
通讯作者:
Counsell, Serena J.
Counsell, Serena J.
中科院分区:
医学4区
文献类型:
--
作者:
Dudink, Jeroen;Kerr, Jenny L.;Counsell, Serena J.

文献摘要

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白色物质损伤和异常成熟被认为是早产儿童和青少年神经发育障碍的主要原因。早期发现白色物质成熟异常对于早产儿的预防、保护和康复策略的设计是非常重要的,弥散张量成像(DTI)可以无创、在体可视化和定量白色物质束,并已成为评估早产儿白色物质成熟的有价值的工具。我们将回顾使用DTI研究早产儿脑中白色物质成熟和损伤(C)2008爱思唯尔爱尔兰有限公司保留所有权利。
White matter injury and abnormal maturation are thought to be major contributors to the neurodevelopmental disabilities observed in children and adolescents who were born preterm. Early detection of abnormal white matter maturation is important in the design of preventive, protective, and rehabilitative strategies for the management of the preterm infant.Diffusion Tensor Imaging (DTI) allows non-invasive, in vivo visualization and quantification of white matter tracts and has become a valuable tool in assessing white matter maturation in children born preterm. We will review the use of DTI to study white matter maturation and injury in the preterm brain (C) 2008 Elsevier Ireland Ltd. All rights reserved.