Bone Augmented With Allograft Onlays for Implant Placement Could Be Comparable With Native Bone

Bone Augmented With Allograft Onlays for Implant Placement Could Be Comparable With Native Bone
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DOI:
10.1016/j.joms.2015.06.151
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发表时间:
2015-11-01
影响因子:
1.9
通讯作者:
Tamimi, Faleh
Tamimi, Faleh
中科院分区:
医学4区
文献类型:
--
作者:
Al-Abedalla, Khadijeh;Torres, Jesus;Tamimi, Faleh

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目的:同种异体骨移植体在牙槽骨增强中具有广阔的应用前景。然而,文献中没有可比较的队列研究表明植入同种异体移植体的骨是否与植入原生牙槽骨的成功率相当。该队列研究的目的是研究同种异体移植体增强骨的质量是否足以放置牙种植体,并达到与未移植骨相当的成功率。材料和方法:两项队列研究分别在46例和369例患者中进行。在第一项研究中,使用组织学技术评估了同种异体移植的骨增强的质量和数量(21例患者接受68个同种异体移植),并与原生牙槽骨(25例患者)进行了比较。在第二项研究中,对植入同种异体骨(16例)的种植体的性能进行了评估,并与植入自体骨(43例)和原生牙槽骨(310例)的种植体进行了比较。结果:第一项研究显示同种异体牙槽骨与原生牙槽骨在骨体积上无显著差异(P = 0.33)。第二项研究显示,植入原生骨(95.8%)、自体骨(96.4%)和同种异体骨(96.8%)的成功率相似。结论:同种异体移植增强骨的数量和质量与宿主原生牙槽骨相似,同种异体移植种植体的成功率与自体移植种植体或原生牙槽骨种植体的成功率相当。(C) 2015年美国口腔颌面外科医师协会
Purpose: Bone allograft onlays have great potential in alveolar bone augmentation. However, no comparable cohort study is available in the literature showing whether implants placed in bone augmented with allograft onlays would have a success rate comparable to those placed in native alveolar bone. The objective of the cohort study was to investigate whether the quality of bone augmented with allograft onlays was sufficient to place dental implants and achieve success rates comparable to those in un-grafted bone.Materials and Methods: Two cohort studies were performed in 46 and 369 patients, respectively. In the first study, the quality and quantity of bone augmented with allograft onlays (21 patients received 68 allograft onlays) were assessed and compared with those of native alveolar bone (25 patients) using histologic techniques. In the second study, the performance of implants placed in allograft-augmented bone (16 patients) was assessed and compared with implants placed in autograft-augmented bone (43 patients) and native alveolar bone (310 patients).Results: The first study showed no significant differences (P = .33) in bone volume between bone augmented with allograft onlay and native alveolar bone. The second study showed that the success rates of implants placed in native bone (95.8%), autograft-augmented bone (96.4%), and allograft-augmented bone (96.8%) were similar to one another.Conclusion: The quantity and quality of allograft-augmented bone are similar to those of host native alveolar bone, and the success rate of implants placed in allograft onlays is comparable to those placed in autograft onlays or native alveolar bone. (C) 2015 American Association of Oral and Maxillofacial Surgeons