Diagnosis and treatment in the early illness phase of bipolar disorders

Diagnosis and treatment in the early illness phase of bipolar disorders
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DOI:
10.1007/s00406-008-5009-z
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发表时间:
2008-11-01
影响因子:
4.7
通讯作者:
Pfennig, Andrea
Pfennig, Andrea
中科院分区:
医学2区
文献类型:
--
作者:
Bauer, Michael;Juckel, Georg;Pfennig, Andrea

文献摘要

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长期未被发现的疾病和显著的心理社会损害的结合使得早期识别和干预在双相情感障碍中起着至关重要的作用。早期发现是从一开始就进行适当教育和治疗的基础。一些证据表明,双相情感障碍发展的早期阶段的特征是可行的。双相情感障碍发展的危险因素已经确立,躁狂前驱症状的特征已经足够长,可以识别和潜在干预。需要建立专门关注双相情感障碍早期发现和预防的中心。这一领域的更多研究是必要的,包括两组有症状的受试者和无症状的人,有和没有积极的家族史。
The combination of a long undetected illness and significant psychosocial impairment renders early identification and intervention a vital role in bipolar disorders. Early detection forms the basis for adequate education and for treatment from the beginning. Several lines of evidence indicate that the characterization of early phases in the development of bipolar disorders is feasible. Risk factors for the development of bipolar disorders have been established and a manic prodrome has been characterized that is sufficiently long to allow recognition and, potentially, intervention. Centers specifically focussing on early detection and prevention of bipolar disorders need to be established. More research in this field is warranted including both groups of symptomatic subjects and symptom-free persons, with and without a positive family history.