The prefrontal landscape: Implications of functional architecture for understanding human mentation and the central executive
The prefrontal landscape: Implications of functional architecture for understanding human mentation and the central executive
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DOI：
10.1098/rstb.1996.0129
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发表时间：
1996-10-29
期刊：
影响因子：
--
通讯作者：
GoldmanRakic, PS
中科院分区：
文献类型：
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作者：
GoldmanRakic, PS
前额叶皮层的功能结构是我们理解人类心理和认知能力的核心。一方面，大脑的这个区域通常被认为是一个未分化的结构，另一方面，它被认为是心理机能的马赛克。本文将工作记忆处理器作为前额叶皮层的一个专门化，并认为前额叶皮层内的不同区域代表了该功能在不同信息域的迭代，包括空间认知、对象认知以及人类的语义处理。根据这种并行处理架构，“中央执行器”可以被认为是多个特定领域处理器交互操作的紧急属性。这些处理器是不同前额皮质区域的专门化，每个处理器都与皮层后部区域的领域相关的长期存储位点和适当的输出通路相互连接。
The functional architecture of prefrontal cortex is central to our understanding of human mentation and cognitive prowess. This region of the brain is often treated as an undifferentiated structure, on the one hand, or as a mosaic of psychological faculties, on the other. This paper focuses on the working memory processor as a specialization of prefrontal cortex and argues that the different areas within prefrontal cortex represent iterations of this function for different information domains, including spatial cognition, object cognition and additionally, in humans, semantic processing. According to this parallel processing architecture, the 'central executive' could be considered an emergent property of multiple domain-specific processors operating interactively. These processors are specializations of different prefrontal cortical areas, each interconnected both with the domain-relevant long-term storage sites in posterior regions of the cortex and with appropriate output pathways.