Diagnosis and Treatment of Idiopathic Normal Pressure Hydrocephalus
Diagnosis and Treatment of Idiopathic Normal Pressure Hydrocephalus
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特发性正常压脑积水的诊治
DOI：
10.1097/01376517-200704000-00007
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发表时间：
2007
影响因子：
2.3
通讯作者：
Vincent M. Vacca
中科院分区：
文献类型：
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作者：
Vincent M. Vacca
特发性正常压力性脑积水(INPH)的特征是典型的三重症状，包括痴呆、尿失禁和步态障碍。大多数患者在第六或第七个年龄段被临床诊断为INPH。许多老年人被误诊为帕金森氏症和痴呆症等疾病，而他们的症状实际上是由INPH引起的。随着预期寿命的增加，准确诊断和有效治疗这些受影响个人的必要性将变得更加具有挑战性。INPH的诊断具有挑战性，需要结合临床体征和症状、放射学表现和诊断测试。对疑似INPH患者进行评估和测试的目的是确定外科手术植入脑室腹膜分流术是否有益。VP分流术现在是一种常见的神经外科手术，但它与风险和并发症有关，这使得对“分流反应”的评估是必要的。
&NA; Idiopathic normal pressure hydrocephalus (INPH) is characterized by a classic triad of symptoms including dementia, urinary incontinence, and gait disturbance. INPH is clinically diagnosed in most patients during the sixth or seventh decade of life. Many older adults are incorrectly diagnosed with disorders such as Parkinson's disease and dementia when their symptoms are actually caused by INPH. As life expectancy increases, the necessity of accurately diagnosing and effectively treating these affected individuals will become more challenging. The diagnosis of INPH is challenging and requires a combination of clinical signs and symptoms, radiographic findings, and diagnostic testing. The purpose of evaluation and testing of individuals with suspected INPH is to determine if surgical implantation of a ventriculoperitoneal (VP) shunt will be beneficial. VP shunting is now a common neurosurgical procedure, but it is one associated with risks and complications, which makes evaluation of “shunt‐responsiveness” essential.