Lacrimal Gland and Salivary Gland Lesions
Lacrimal Gland and Salivary Gland Lesions
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泪腺和唾液腺病变
DOI：
10.1007/978-4-431-54228-5_23
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发表时间：
2014
影响因子：
1.9
通讯作者：
Y. Shinomura
中科院分区：
文献类型：
--
作者：
M. Yamamoto;H. Takahashi;Y. Shinomura
组织活检对诊断IgG 4相关泪腺炎和涎腺炎具有重要的诊断价值。它们不仅为诊断提供了依据之一，还有助于恶性淋巴瘤等疾病的鉴别。在IgG 4相关泪腺炎和涎腺炎中，与其他类型的IgG 4相关疾病（IgG 4-RD）一样，显著的淋巴浆细胞浸润和纤维化均为特征性组织病理学结果。组织内的浆细胞群由过量的IgG 4阳性细胞组成，并且IgG 4：总IgG比率通常超过0.40。在组织内也发现许多淋巴滤泡。与自身免疫性胰腺炎相比，通常被视为IgG 4-RD的典型组织病理学特征的Storiform纤维化和闭塞性静脉炎在唾液腺和泪腺中可能不太常见。因此，观察到IgG 4-RD病理学特征的一些器官间变异性。
Tissue biopsies undertaken to diagnose IgG4-related dacryoadenitis and sialadenitis are of great diagnostic value. Not only do they provide one of the bases for the diagnosis, they also facilitate the differentiation of conditions such as malignant lymphoma. In IgG4-related dacryoadenitis and sialadenitis, as in other types of IgG4-related disease (IgG4-RD), both a marked lymphoplasmacytic infiltrate and fibrosis are characteristic histopathological findings. The plasma cell population within tissue is comprised of an overabundance of IgG4-positive cells, and the IgG4:total IgG ratio is typically in excess of 0.40. Numerous lymph follicles are also found within tissues. Storiform fibrosis and obliterative phlebitis, generally viewed as typical histopathological features of IgG4-RD, are perhaps less common in the salivary and lacrimal glands compared to autoimmune pancreatitis. Thus, some organ-to-organ variability in the pathological features of IgG4-RD is observed.
一种新的临床实体，IgG4 相关疾病 (IgG4RD)：一般概念和细节。
影响因子：
2.2
作者：
Umehara, Hisanori;Okazaki, Kazuichi;Masaki, Yasufumi;Kawano, Mitsuhiro;Yamamoto, Motohisa;Saeki, Takako;Matsui, Shoko;Sumida, Takayuki;Mimori, Tsuneyo;Tanaka, Yoshiya;Tsubota, Kazuo;Yoshino, Tadashi;Kawa, Shigeyuki;Suzuki, Ritsuro;Takegami, Tsutomu;Tomosugi, Naohisa;Kurose, Nozomu;Ishigaki, Yasuhito;Azumi, Atsushi;Kojima, Masaru;Nakamura, Shigeo;Inoue, Dai
通讯作者：
Inoue, Dai
影响因子：
5.6
作者：
Kitagawa, S;Zen, Y;Nakanuma, Y
通讯作者：
Nakanuma, Y
影响因子：
13.5
作者：
Zen, Yoh;Fujii, Takahiko;Nakanuma, Yasuni
通讯作者：
Nakanuma, Yasuni