Beyond the SNARE: Munc18-1 chaperones α-synuclein.
Beyond the SNARE: Munc18-1 chaperones α-synuclein.
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超越圈套:Munc18-1 伴侣α-突触核蛋白。
DOI:
10.1083/jcb.201608060
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发表时间:
2016
期刊:
影响因子:
--
通讯作者:
Rodal,AvitalA
中科院分区:
文献类型:
--
作者:
Deshpande,Mugdha;Rodal,AvitalA
Early infantile epileptic encephalopathy (EIEE)–associated mutations in MUNC18-1 cause Munc18-1 misfolding and cellular aggregation. In this issue, Chai et al. (2016. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201512016) find that Munc18-1 is a molecular chaperone for α-synuclein and that aggregated Munc18-1 EIEE-causing mutants promote α-synuclein aggregation.
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8.3
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期刊:
The American journal of physiology
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DOI:
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发表时间:
1984
期刊:
The American journal of physiology
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