Increased Pain Reporting by Head and Neck Cancer Patients at Radiation Oncology Consultation: A Quality-of-Life Analysis.
Increased Pain Reporting by Head and Neck Cancer Patients at Radiation Oncology Consultation: A Quality-of-Life Analysis.
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头颈癌患者在放射肿瘤学咨询中报告的疼痛增加：生活质量分析。
DOI：
10.1002/lary.28784
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发表时间：
2021
期刊：
影响因子：
--
通讯作者：
Takiar,Vinita
中科院分区：
文献类型：
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作者：
Havard,Molly;Esslinger,Hope;Mierzwa,Michelle;Kharofa,Jordan;Takiar,Vinita
头颈部恶性肿瘤（Head and Neck Cancers，HNC）是一种发病率较高的肿瘤.生活质量（QoL）分析有助于理解影响患者体验的主观因素。在这里，我们评估了2015年在一家机构进行的首次放射肿瘤咨询时与疼痛报告增加相关的患者和/或肿瘤因素。研究设计前瞻性横断面问卷调查研究方法2015年所有新的患者咨询都提供了欧洲癌症研究和治疗组织生活质量问卷核心30（EORTC QLQ-C30）调查。HNC患者还获得了EORTC QLQ-HN 35模块。对完成调查的患者进行回顾性病历审查。分析患者人口统计学、肿瘤特征和QoL反应的潜在相关性。使用SAS v9.4（SAS研究所，卡里，NC）进行统计分析，与P <0.05被认为是significant.ResultsOf 771新的患者咨询，137咨询HNC患者。其中，62名患者完成了两项调查。HNC患者报告的疼痛程度高于所有其他疾病部位（比值比[OR]：2.05;P<0.01）。在EORTC QLQ-C30数据的单变量分析中，发现疼痛增加与肿瘤大小> 4 cm相关（OR：3.05;P≤ .05）。EORTC QLQ-HN 35数据显示淋巴结受累与疼痛独立相关（OR：3.12;P≤ .05）。多变量分析显示，疼痛增加与就诊时未开止痛药（P≤ .05）和年龄≥ 65岁（P≤ .05）有关。结论HNC患者就诊时疼痛明显多于其他原发性恶性肿瘤患者。了解导致主观疼痛的因素可能使医疗服务提供者能够主动解决这些症状，以改善患者的QoL。证据等级2c-结局研究。喉镜，131：326-332，2021
ObjectivesHead and neck cancers (HNC) are associated with significant morbidity. Quality‐of‐life (QoL) analyses can assist with understanding subjective factors shaping the patient experience. Here, we assess for patient and/or tumor factors associated with increased pain reporting at the time of initial radiation oncology consultation at a single institution in 2015.Study DesignProspective cross‐sectional questionnaire research.MethodsAll new patient consultations in 2015 were offered the European Organization for Research and Treatment of Cancer Quality‐of‐Life Questionnaire Core‐30 (EORTC QLQ‐C30) survey. HNC patients were also offered the EORTC QLQ‐HN35 module. Retrospective chart review was performed on patients who completed the surveys. Patient demographics, tumor characteristics, and QoL responses were analyzed for potential associations. Statistical analyses were conducted using SAS v9.4 (SAS Institute, Cary, NC), withP< .05 considered significant.ResultsOf 771 new patient consultations, 137 consultations were for HNC patients. Of those, 62 patients completed both surveys. HNC patients reported greater pain relative to all other disease sites (odds ratio [OR]: 2.05;P< .01). On univariate analysis of the EORTC QLQ‐C30 data, increased pain was found to be associated with tumor size > 4 cm (OR: 3.05;P≤ .05). The EORTC QLQ‐HN35 data revealed lymph node involvement to be independently associated with pain (OR: 3.12;P≤ .05). On multivariate analysis, increased pain was associated with lack of pain medication prescription at the time of consultation (P≤ .05) and age ≥ 65 years (P≤ .05).ConclusionPatients with HNC reported significantly more pain at consultation than patients with other primary malignancies. Understanding factors contributing to subjective pain may allow providers to potentially address these symptoms proactively to improve patients’ QoL.Level of Evidence2c – Outcomes research.Laryngoscope, 131:326–332, 2021