Receptive fields of cerebellar cells receiving exteroceptive input in a Gymnotid fish.
Receptive fields of cerebellar cells receiving exteroceptive input in a Gymnotid fish.
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裸鱼中接受外感受输入的小脑细胞的感受野。
DOI：
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发表时间：
1975
影响因子：
2.5
通讯作者：
J. Bastian
中科院分区：
文献类型：
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作者：
J. Bastian
弱电鱼类无尾鱼小脑尾叶的单个神经元对该动物产生的正常电场的扭曲做出反应。移动塑料或金属物体，以及一个更简单的刺激，一个移动的电偶极子，都会产生足够的鱼场扭曲，使小脑细胞做出反应。移动的偶极子刺激了鱼皮肤上足够小的区域，这是由单个电感受器的反应决定的，可以产生单个小脑细胞的感受野地图。从相对较小的兴奋区或抑制区到包含多个兴奋区和抑制区的较大区域，感受野的复杂性变化很大，通常彼此相邻。大多数被研究的细胞都表现出方向性反应。通常，不同的反应是由相反的运动方向引起的，而在与引起反应的方向相反的运动中没有反应的单位较少；改变刺激运动的速度只会引起小脑细胞反应的微小变化；然而，对已知对运动刺激有反应的皮肤区域施加静止刺激会产生对该区域适当标志的较弱反应。运动似乎是这些细胞刺激的一个重要组成部分。也可以看到对视觉和电感受性输入都有反应的细胞。对上述两种方式的反应各不相同。从频繁显示的突发性放电中记录到的细胞与其他低等脊椎动物的浦肯野细胞产生的放电相似，而且大多数研究的细胞被认为是浦肯野细胞。体视学研究发现，鱼体内感受野中心的位置与细胞在大脑中的位置之间存在体视性关系。所有获得的结果都与小脑尾叶正在处理与物体检测相关的电接受信息的假设相一致。
Single neurons in the caudal lobe of the cerebellum of the weakly electric fish Apteronotus albifrons respond to distortions in the normal electric field produced by the animal. Moving plastic or metal objects as well as a simpler stimulus, a moving electrical dipole, produce adequate distortions of the fish's field to cause the cerebellar cells to respond. The moving dipole stimulated small enough areas of the fish's skin, as determined by the responses of single electroreceptors, to allow maps of the receptive fields of single cerebellar cells to be produced. The receptive fields seen varied widely in complexity from relatively small excitatory or inhibitory areas to larger fields containing multiple excitatory and inhibitory areas usually bordering one another. Most cells studied displayed directional responses. Usually qualitatively different responses resulted from opposite directions of movement, and less frequently units were seen in which no response resulted from movement opposite the direction which caused responses; Varying the rate of stimulus movement caused only small changes in the responses of cerebellar cells; however, motionless stimuli applied over areas of skin known to respond to moving stimuli produced weaker responses of the appropriate sign for that area. Movement seems to be an important component of the stimulus for these cells. Cells were also seen which responded to visual as well as to electroreceptive input. Responses to each of these two modalities presented above were quite different. The cells recorded from frequently displayed burst discharges similar to those produced by Purkinje cells in other lower vertebrates, and most of the cells studied are believed to be Purkinje cells. A somatotopic relationship was found between the position of the center of a receptive field on the fish's body and the position of the cell in the brain. All of the results obtained are compatible with the hypothesis that the caudal lobe of the cerebellum is processing electroreceptive information related to object detection.