Effects of a 7-day eccentric training period on muscle damage and inflammation
Effects of a 7-day eccentric training period on muscle damage and inflammation
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DOI：
10.1097/00005768-200110000-00018
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发表时间：
2001-10-01
期刊：
影响因子：
--
通讯作者：
Hsieh, SS
中科院分区：
文献类型：
--
作者：
Chen, TC;Hsieh, SS
目的：本研究探讨了 7 天重复最大等速离心训练对肌肉损伤和炎症反应指标的影响。方法：22 名大学年龄男性被随机分配到离心训练组 (ET) (N = 12) 和对照组 (CON) (N = 10)。初始练习是使用 Cybex 6000 以 60 度 .s(-1) 角速度在非优势肘屈肌上重复 30 次最大自主等速偏心收缩 (ECC1)。 ET组在ECC1之后连续6天（称为ECC2至ECC7）进行相同的运动。在 ECC1 之前、之后立即和每 24 小时测量一次 ECC1 后连续 7 天的上臂围 (CIR)、运动范围 (ROM) 和最大等长力 (MIF)。之前评估血浆肌酸激酶（CK）、乳酸脱氢酶（LDH）、谷草酰乙酸转氨酶（GOT）、白细胞计数以及血清白介素-1β和-6（IL-1β、IL-6）水平； 2 小时；以及 ECC1 后 1、3、4、6 和 7 天。在 ECC1 之前和之后连续 7 天测量肌肉酸痛程度。结果：ECC1 在两组的大多数指标中均产生显着变化（P < 0.05），但白细胞计数除外（P > 0.05）。 ET 组从 ECC2 到 ECC7 没有发现损伤增加的指标（P > 0.05）。结论：对受损肌肉进行连续强化等速离心训练并不会加剧 ECC1 后的肌肉损伤和炎症。此外，肌肉“适应效应”最早可能在ECC1后24小时就出现，如ET组在ECC1后连续6天的表现所示。
Purpose: This study examined the effects of a 7-d repeated maximal isokinetic eccentric training period on the indicators of muscle damage and inflammatory response. Methods: Twenty-two college-age males were randomly assigned to eccentric training (ET) (N = 12) and control groups (CON) (N = 10). The initial exercise was 30 repetitions of maximal voluntary isokinetic eccentric contraction (ECC1) on nondominant elbow flexors with Cybex 6000 at 60 degrees .s(-1) angular velocity. The ET group performed the same exercise for the following 6 consecutive days (referred to as ECC2 to ECC7) after ECC1. Upper arm circumference (CIR), range of motion (ROM), and maximal isometric force (MIF) were measured before, immediately after, and every 24 h for 7 consecutive days after ECC1. Plasma creatine kinase (CK), lactate dehydrogenase (LDH), glutamic oxaloacetate transaminase (GOT), leukocyte counts, and serum interleukin-1 beta and -6 (IL-1 beta, IL-6) levels were assessed before; at 2 h; and at 1, 3, 4, 6, and 7 d after ECC1. Muscle soreness was measured before and for 7 consecutive days after ECC1. Results: The ECC1 produced significant changes in most of the measures for both groups (P < 0.05), with the exception of leukocyte counts (P > 0.05). No indicators of increased damage (P > 0.05) were found from ECC2 to ECC7 for the ET group. Conclusion: Continuous intensive isokinetic eccentric training performed with damaged muscles did not exacerbate muscle damage and inflammation after ECC1. In addition, a muscular "adaptation effect" may occur as early as 24 h after ECC1, as shown by the ET group's performance for 6 consecutive days after ECC1.