Accuracy of prenatal smoking data from Washington State birth certificates in a population-based sample with cotinine measurements.
Accuracy of prenatal smoking data from Washington State birth certificates in a population-based sample with cotinine measurements.
复制标题
DOI：
10.1016/j.annepidem.2013.12.008
复制
发表时间：
2014-03
影响因子：
5.6
通讯作者：
Mueller BA
中科院分区：
文献类型：
--
作者：
Searles Nielsen S;Dills RL;Glass M;Mueller BA
评估当代美国出生证明中吸烟数据的准确性。我们比较了2007年出生的200名婴儿（其中100名随机选择自认为不吸烟的婴儿和100名自认为吸烟的婴儿）在华盛顿州出生证明上报告的产前吸烟数据和新生儿筛查干血点中测量的可替宁数据。我们估计了出生证明数据识别产前吸烟者的敏感性，以及自我认定的妊娠晚期吸烟者报告吸烟水平的准确性。2位（2%）报告在怀孕期间不吸烟的母亲所生婴儿的全血可替宁浓度与母亲主动吸烟相符（敏感性85%）。出生证明识别报告吸烟者在整个怀孕期间继续吸烟的敏感性相似（89%）。在分娩后不久收集婴儿样本的自我认定的妊娠晚期吸烟者中，婴儿可替宁与母亲报告的妊娠晚期吸烟/天之间的Spearman rho为0.54。在流行病学研究中，出生证明可能是评估产前吸烟状况的可行选择，也可能是评估吸烟者戒烟和剂量的可行选择，如果有足够的能力克服适度的暴露测量误差。
To assess the accuracy of smoking data in contemporary U.S. birth certificates. We compared data on prenatal smoking as reported on Washington State birth certificates to cotinine measured in archived newborn screening dried blood spots for 200 infants born in 2007 (100 randomly selected from births to self-reported non-smokers and 100 born to self-reported smokers). We estimated the sensitivity of the birth certificate data to identify prenatal smokers, and the precision with which self-identified third trimester smokers report smoking levels. Infants born to 2 (2%) mothers who reported they did not smoke during the pregnancy had whole blood cotinine concentrations consistent with active smoking by the mother (sensitivity 85%). Sensitivity of the birth certificate to identify reported smokers who continued to smoke throughout pregnancy was similar (89%). Among self-identified third trimester smokers whose infants' specimens were collected shortly after delivery, Spearman's rho between infant cotinine and maternal-reported cigarettes/day in the third trimester was 0.54. Birth certificates may represent a viable option for assessing prenatal smoking status, and possibly smoking cessation and dose among smokers, in epidemiologic studies sufficiently powered to overcome a moderate amount of exposure measurement error.