Daily use of nicotine replacement medications is related to daily smoking status: An ecological momentary assessment study.
Daily use of nicotine replacement medications is related to daily smoking status: An ecological momentary assessment study.
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DOI：
10.1016/j.drugalcdep.2021.109161
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发表时间：
2021-12-01
影响因子：
4.2
通讯作者：
Businelle MS
中科院分区：
文献类型：
--
作者：
Hébert ET;Bhushan T;Ra CK;Frank-Pearce S;Alexander AC;Cole AB;Kendzor DE;Businelle MS
很少有研究探讨每天坚持尼古丁替代疗法 (NRT) 如何影响日常戒烟。使用基于智能手机的戒烟干预试点随机对照试验的数据。单独的广义线性混合模型研究了 NRT 使用的生态瞬时评估与当天和第二天吸烟状况之间的关联。单独的模型检查了日常吸烟状况与 1）任何 NRT 的使用、2）尼古丁口香糖的使用量和 3）尼古丁贴片佩戴时间之间的关系。还检查了不遵守药物治疗的原因。参与者 (n=77) 主要是白人 (66.2%) 和女性 (50.6%)，平均年龄 50.4 岁 (SD=11.6)，基线时平均每天吸 21.8 支香烟 (SD=11.0)。每日使用 NRT 与当天和第二天吸烟的可能性降低显着相关。虽然同时使用口香糖和贴片以及单独使用贴片与当天和第二天吸烟的几率降低有关，但单独使用口香糖与吸烟几率的降低没有显着相关。最常提到的不使用贴剂或口香糖的原因是“其他”（43.3%），其次是“副作用”（27.1%）和“忘记”（18.9%）。每天使用贴剂或同时使用贴剂和口香糖可以降低日常吸烟的风险。单独使用低水平的尼古丁口香糖可能不是有效的戒烟策略。未来的研究应进一步探讨 NRT 不依从性的原因以及提高 NRT 依从性的方法。
Few studies have examined how daily adherence to nicotine replacement therapy (NRT) impacts daily smoking abstinence. Data from a pilot randomized controlled trial of a smartphone-based smoking cessation intervention were used. Separate, generalized linear mixed models examined the association between ecological momentary assessments of NRT use and same-day and next day smoking status. Separate models examined the relationship between daily smoking status and 1) any use of NRT, 2) quantity of nicotine gum used, and 3) nicotine patch wear time. Reasons for medication non-adherence were also examined. Participants (n=77) were predominantly White (66.2%) and female (50.6%), 50.4 years old (SD=11.6) on average, and they smoked an average of 21.8 cigarettes per day (SD=11.0) at baseline. Daily NRT use was significantly associated with a lower likelihood of smoking both within that same day and the following day. While using the gum and patch together, and using the patch alone were associated with reduced odds of same-day and next-day smoking, using the gum alone was not significantly associated with reduced odds of smoking. The most commonly cited reasons for not using the patch or gum was “other” (43.3%), followed by “side effects” (27.1%), and “forgot” (18.9%). Daily use of the patch or both the patch and gum was associated with a lower risk of daily smoking. Low levels of nicotine gum use alone may not be an effective cessation strategy. Future studies should further explore reasons for NRT non-compliance, and ways to increase NRT adherence.
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影响因子：
33.9
作者：
Babb, Stephen;Malarcher, Arm;Jamal, Ahmed
通讯作者：
Jamal, Ahmed
影响因子：
7.4
作者：
Hebert, Emily T.;Ra, Chaelin K.;Businelle, Michael S.
通讯作者：
Businelle, Michael S.
影响因子：
3.4
作者：
Schlam, Tanya R.;Cook, Jessica W.;Piper, Megan E.
通讯作者：
Piper, Megan E.
影响因子：
4.7
作者：
Schlam, Tanya R.;Baker, Timothy B.;Piper, Megan E.
通讯作者：
Piper, Megan E.
影响因子：
4.2
作者：
Ma, Ping;Kendzor, Darla E.;Businelle, Michael S.
通讯作者：
Businelle, Michael S.