Fluid-Structure Interaction Simulation of Prosthetic Aortic Valves: Comparison between Immersed Boundary and Arbitrary Lagrangian-Eulerian Techniques for the Mesh Representation.
Fluid-Structure Interaction Simulation of Prosthetic Aortic Valves: Comparison between Immersed Boundary and Arbitrary Lagrangian-Eulerian Techniques for the Mesh Representation.
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DOI：
10.1371/journal.pone.0154517
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发表时间：
2016
期刊：
影响因子：
3.7
通讯作者：
Segers P
中科院分区：
文献类型：
--
作者：
Bavo AM;Rocatello G;Iannaccone F;Degroote J;Vierendeels J;Segers P
近年来，FSI（流体-结构相互作用）模拟在心脏瓣膜流体力学分析中的作用变得越来越重要，能够捕获血液与周围生物组织和瓣膜本身之间的相互作用。在设置FSI模拟时，必须做出几种选择以选择最适合感兴趣情况的方法：特别是，为了模拟柔性瓣叶心脏瓣膜，流体域的离散化类型至关重要，可以用ALE（任意拉格朗日-欧拉）或欧拉公式描述。大多数报告的3D心脏瓣膜FSI模拟是用欧拉公式进行的，允许域的大变形而不影响流体网格的质量。然而，已知的是，ALE-FSI方法保证在固体和流体之间的界面处的更准确的结果。本文的目的是描述相同的主动脉瓣模型在这两种情况下，比较性能的ALE为基础的FSI解决方案和欧拉为基础的FSI方法。在第一个简化的2D病例后，在完整的3D设置中考虑主动脉几何结构。模型在两种设置中尽可能保持相似，以更好地比较模拟结果。尽管对于2D情况，差异并不大，但根据我们的经验，完整3D ALE-FSI模拟的性能受到ALE公式固有的技术问题和要求的显着限制，主要与流体域的网格运动和变形有关。作为这项工作的次要成果，重要的是要指出，求解器的选择也影响最终结果的可靠性。
In recent years the role of FSI (fluid-structure interaction) simulations in the analysis of the fluid-mechanics of heart valves is becoming more and more important, being able to capture the interaction between the blood and both the surrounding biological tissues and the valve itself. When setting up an FSI simulation, several choices have to be made to select the most suitable approach for the case of interest: in particular, to simulate flexible leaflet cardiac valves, the type of discretization of the fluid domain is crucial, which can be described with an ALE (Arbitrary Lagrangian-Eulerian) or an Eulerian formulation. The majority of the reported 3D heart valve FSI simulations are performed with the Eulerian formulation, allowing for large deformations of the domains without compromising the quality of the fluid grid. Nevertheless, it is known that the ALE-FSI approach guarantees more accurate results at the interface between the solid and the fluid. The goal of this paper is to describe the same aortic valve model in the two cases, comparing the performances of an ALE-based FSI solution and an Eulerian-based FSI approach. After a first simplified 2D case, the aortic geometry was considered in a full 3D set-up. The model was kept as similar as possible in the two settings, to better compare the simulations’ outcomes. Although for the 2D case the differences were unsubstantial, in our experience the performance of a full 3D ALE-FSI simulation was significantly limited by the technical problems and requirements inherent to the ALE formulation, mainly related to the mesh motion and deformation of the fluid domain. As a secondary outcome of this work, it is important to point out that the choice of the solver also influenced the reliability of the final results.