Substance Use Following Bariatric Weight Loss Surgery

Substance Use Following Bariatric Weight Loss Surgery
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DOI:
10.1001/2013.jamasurg.265
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发表时间:
2013-02-01
期刊:
影响因子:
16.9
通讯作者:
Geliebter, Allan
Geliebter, Allan
中科院分区:
医学1区
文献类型:
--
作者:
Conason, Alexis;Teixeira, Julio;Geliebter, Allan

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目的:评估减肥手术(WLS)前后的物质使用情况。有一个研究调查肥胖WLS后物质使用的发生率很少。假设接受WLS的患者会表现出物质使用的增加(药物使用、酒精使用和吸烟)以补偿手术后明显减少的食物摄入。设计:前瞻性研究。设置:一家主要的城市社区医院。参与者:共有155名参与者(132名女性和23名男性)接受WLS的患者是从减肥手术中心的术前信息会议中招募的。参与者接受腹腔镜Roux-en-Y胃旁路手术(n = 100)或腹腔镜可调节胃束带手术(n = 55)。参与者在术前基线和术后1、3、6、12和24个月完成问卷调查以评估饮食行为和物质使用。主要结果测量:通过强迫行为问卷评估物质使用。参与者报告说,(药物使用、酒精使用和吸烟的复合物,下文称为复合物质使用)手术后24个月。具体而言,参与者在手术后24个月内使用复合物质的频率从基线显著增加(P = 0.02),在手术后1个月、3个月和6个月至24个月内也显著增加(均P
Objective: To assess substance use before and after bariatric weight loss surgery (WLS). There is a paucity of research investigating the occurrence of substance use following bariatric WLS. It was hypothesized that patients who underwent WLS would exhibit an increase in substance use (drug use, alcohol use, and cigarette smoking) following surgery to compensate for a marked decrease in food intake.Design: Prospective study.Setting: A major urban community hospital.Participants: A total of 155 participants (132 women and 23 men) who underwent WLS were recruited from a preoperative information session at a bariatric surgery center.Intervention: Participants received either laparoscopic Roux-en-Y gastric bypass surgery (n = 100) or laparoscopic adjustable gastric band surgery (n = 55). Participants completed questionnaires to assess eating behaviors and substance use at preoperative baseline and 1, 3, 6, 12, and 24 months after surgery.Main Outcome Measure: Substance use as assessed by the Compulsive Behaviors Questionnaire.Results: Participants reported significant increases in the frequency of substance use (a composite of drug use, alcohol use, and cigarette smoking, hereafter referred to as composite substance use) 24 months after surgery. Specifically, participants experienced a significant increase in the frequency of composite substance use from baseline to 24 months after surgery (P =.02), as well as significant increases from 1 month, 3 months, and 6 months to 24 months after surgery (all P