UNCONSTRAINED BACTERIAL PROMISCUITY - THE TN916-TN1545 FAMILY OF CONJUGATIVE TRANSPOSONS
UNCONSTRAINED BACTERIAL PROMISCUITY - THE TN916-TN1545 FAMILY OF CONJUGATIVE TRANSPOSONS
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DOI：
10.1016/s0966-842x(00)88930-1
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发表时间：
1995-06-01
影响因子：
15.9
通讯作者：
JAWORSKI, DD
中科院分区：
文献类型：
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作者：
CLEWELL, DB;FLANNAGAN, SE;JAWORSKI, DD
共轭转座子是在细菌世界中普遍存在的元素。Tn916-Tn1545家族成员携带广泛传播的四环素耐药决定因素Tet M，以及其他耐药基因。它们已经在50多个不同的物种和24个属的细菌中被发现或被引入。最近的研究对这些有趣的可移动元素的运动的分子基础有了深入的了解。
Conjugative transposons are highly ubiquitous elements found throughout the bacterial world. Members of the Tn916-Tn1545 family carry the widely disseminated tetracycline-resistance determinant Tet M, as well as additional resistance genes. They have been found naturally in, or been introduced into, over 50 different species and 24 genera of bacteria. Recent investigations have led to insights into the molecular basis of movement of these interesting mobile elements.