Incidence and prevalence of juvenile arthritis in an urban population of southern Germany:: a prospective study
Incidence and prevalence of juvenile arthritis in an urban population of southern Germany:: a prospective study
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DOI：
10.1136/ard.60.10.940
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发表时间：
2001-10-01
影响因子：
27.4
通讯作者：
Hörmann, A
中科院分区：
文献类型：
--
作者：
von Koskull, S;Truckenbrodt, H;Hörmann, A
为了确定青少年关节炎的发病率和患病率在德国城市population. Methods所有766儿科医生，骨科医生，风湿病学家在实践或门诊诊所在12个德国南部城镇工作，被要求报告所有的患者咨询他们的青少年关节炎在1995年。有持续症状的患者随访9-12个月以获得最终诊断。扩展措施的质量控制采取控制已知的bias.Results-Of 457例报告的情况下，294被诊断为感染帕拉/感染后关节炎（PPA），78与青少年慢性关节炎（伊卡），IS与其他形式的关节炎。一半的PPA病例被归类为髋关节一过性滑膜炎（SH）。对于JCA，报告的年发病率为6.6，患病率为14.8/10万16岁以下受试者。对于PPA，报告的发生率为76例，患病率为每100，000名16岁以下受试者中4.4例。风湿热的发病率明显低于每10万名16岁以下的人中有1人。一个校正模型被用来控制已知的偏见，并调整估计severing. Conclusions的青少年关节炎的发病率和患病率在德国这第一次前瞻性研究的结果是一致的，在柏林地区进行的回顾性研究。根据这些结果，估计德国青少年关节炎的年发病率如下：每年750-900例JCA病例，21000例SH病例，21000例其他形式PPA病例。风湿热的发病病例数预计将明显低于每年150例。预计总患病率为3600-4350例JCA病例，2250-3000例SH病例，以及相同数量的其他形式的PPA。
Objective-To ascertain the incidence and prevalence of juvenile arthritis in a German urban population.Methods-All 766 paediatricians, orthopaedists, and rheumatologists working in practices or outpatient clinics in 12 south German towns were asked to report all patients who consulted them for juvenile arthritis during the year 1995. Patients with continuing symptoms were followed up for 9-12 months to obtain a final diagnosis. Extended measures of quality control were taken to control for known biases.Results-Of 457 reported cases, 294 were diagnosed with para-/postinfectious arthritis (PPA), 78 with juvenile chronic arthritis (ICA), and IS with other forms of arthritis. Half of the PPA cases were classified as transient synovitis of the hip (SH). For JCA the reported annual incidence was 6.6 and the prevalence 14.8 per 100 000 subjects under 16 years of age. For PPA the reported incidence was 76 and the prevalence 4.4 per 100 000 subjects under 16. The incidence of rheumatic fever was clearly below 1 per 100 000 people under 16. A correction model was used to control for known biases and to adjust the estimates accordingly.Conclusions-The results of this first prospective study on the incidence and prevalence of juvenile arthritis in Germany are consistent with a retrospective study performed in the Berlin area. Based on these results it was estimated that the annual frequency of juvenile arthritis in Germany is as follows: 750-900 incident JCA cases, 21 000 incident SH cases, and 21 000 incidence cases of other forms of PPA a year. The number of incidence cases of rheumatic fever is expected to be markedly lower than 150 a year. The total prevalence is expected to be 3600-4350 JCA cases, 2250-3000 SH cases, and the same number of other forms of PPA.