Bifurcaria bifurcata: a key macro-alga as a source of bioactive compounds and functional ingredients
Bifurcaria bifurcata: a key macro-alga as a source of bioactive compounds and functional ingredients
复制标题
DOI：
10.1111/ijfs.13135
复制
发表时间：
2016-07-01
影响因子：
3.3
通讯作者：
Pedrosa, Rui
中科院分区：
文献类型：
--
作者：
Alves, Celso;Pinteus, Susete;Pedrosa, Rui
本工作的目的是研究双叉叉藻的基本组成和生物活性特征。它含有73.31 +/- 0.69%的水分，8.57 +/- 0.11g/100 g干重（d.w.）蛋白质含量为5.81 ± 0.14g/100 g干重。脂肪含量为30.15 ± 0.00g/100 g干重。灰。多不饱和脂肪酸含量最高，为2426.56mg/100 g，占总脂肪酸的41.77%。甲醇提取物中多酚含量高（220.01 ± 0.010间苯三酚当量g（-1）提取物），DPPH自由基还原能力（EC_（50）：58.82gmL（-1））和氧自由基吸收能力（3151.35 ± 119.33molTrolox当量g（-1）提取物）。对铜绿假单胞菌（11.3 +/- 1.5mm）和酿酒酵母（IC_（50）：17.07gmL（-1））的最高抑菌效果分别由甲醇和二氯甲烷馏分诱导。二氯甲烷组分对Caco-2和HepG-2细胞的抗肿瘤活性最高。分叉叉藻是一种很有前途的生物活性物质和功能性成分的来源。
The aim of this work was to study the proximate composition and the bioactive profile of Bifurcaria bifurcata. It contains 73.31 +/- 0.69% of moisture, 8.57 +/- 0.11g per 100g dry weight (d.w.) of protein, 5.81 +/- 0.14g per 100g d.w. of lipid content and 30.15 +/- 0.00g per 100g d.w. of ash. The polyunsaturated fatty acids were the most abundant fatty acid (FA), accounting for 2426.56mg per 100g which represents 41.77% of the total FA. The methanolic fraction showed high quantity of polyphenols (220.01 +/- 0.010 phloroglucinol equivalentsg(-1) extract), DPPH radical reduction capacity (EC50:58.82gmL(-1)) and oxygen radical absorbent capacity (3151.35 +/- 119.33mol Trolox equivalentsg(-1) extract). The highest antimicrobial effect was observed against Pseudomonas aeruginosa (11.3 +/- 1.5mm) and Saccharomyces cerevisiae (IC50:17.07gmL(-1)) induced by methanolic and dichloromethane fractions, respectively. Dichloromethane fraction revealed the highest antitumor activity on Caco-2 and HepG-2 cells. Bifurcaria bifurcata can be a promising source of bioactive compounds and functional ingredients.