Asymmetric transfer hydrogenation catalysed by hydrophobic dendritic DACH-rhodium complex in water.
Asymmetric transfer hydrogenation catalysed by hydrophobic dendritic DACH-rhodium complex in water.
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DOI：
10.1039/b608386b
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发表时间：
2006-08
影响因子：
3.2
通讯作者：
Linfeng Jiang;Tongxing Wu;Yingchun Chen;Jin Zhu;Jin-gen Deng
中科院分区：
文献类型：
--
作者：
Linfeng Jiang;Tongxing Wu;Yingchun Chen;Jin Zhu;Jin-gen Deng
Hydrophobic Fréchet-type dendritic chiral 1,2-diaminocyclohexane-Rh(III) complexes have been applied in the asymmetric transfer hydrogenation of ketones in water using HCOONa as hydrogen source. The catalysts were found to be finely dissolved in the liquid substrates in the aqueous mixture and exhibited high catalytic activity and enantioselectivity (52-97% ee). The catalytic loading could be decreased to 0.01 mol% and good conversion was still obtained with excellent enantioselectivity. Moreover, the catalyst could be easily precipitated from the mixture by adding hexane and reused several times without affecting the high enantioselectivity.
