Feasibility randomised controlled trial of a guided workbook intervention to support work-related goals among cancer survivors in the UK
Feasibility randomised controlled trial of a guided workbook intervention to support work-related goals among cancer survivors in the UK
复制标题
指导工作手册干预的可行性随机对照试验，以支持英国癌症幸存者的工作相关目标
作者：
Elizabeth A Grunfeld;Lauren Schumacher;Maria Armaou;P. Woods;Pauline Rolf;Andrew J Sutton;Anjali Zarkar;Steven S Sadhra
目的疾病后就业与更好的身体和心理功能有关。本研究旨在评估理论上主导的工作簿干预的可行性和可接受性，旨在支持癌症患者重返工作岗位。设计嵌入式定性访谈的随机对照试验。在四个英国国民健康服务信托基金内设置肿瘤诊所。参与者接受乳腺癌、妇科癌、前列腺癌或结直肠癌诊断并接受至少两周治疗的患者。干预一个自我指导的工作计划工作簿，旨在支持癌症患者返回工作岗位，每两周打一次电话，讨论进展情况。对照组像往常一样接受治疗，并在12个月的随访结束时提供练习册。我们评估了可行性的各个方面，包括资格，招募，数据收集，自然减员，方法的可行性，干预的可接受性和计算成本效益的潜力。结果符合条件的患者招募率为44%; 68名参与者同意，58名（85%）完成基线测量。随机化程序是可接受的，数据收集方法（包括成本效益数据）是可行的，干预是可接受的参与者。6个月和12个月随访时的保留率分别为72%和69%。在6个月的随访中，30%的常规护理组已经恢复全职或兼职工作（包括分阶段恢复工作），而干预组为43%。在12个月时，百分比为47%（常规护理）和68%（干预）。结论：研究结果证实了确定性试验的可行性，但需要进一步考虑增加男性和黑人及少数民族癌症患者的参与率。试验注册号ISRCTN 56342476;预结果。
Objectives Employment following illness is associated with better physical and psychological functioning. This study aimed to assess the feasibility and acceptability of a theoretically led workbook intervention designed to support patients with cancer returning to work. Design Parallel-group randomised controlled trial with embedded qualitative interviews. Setting Oncology clinics within four English National Health Service Trusts. Participants Patients who had received a diagnosis of breast, gynaecological, prostate or colorectal cancer and who had been receiving treatment for a minimum of two weeks. Intervention A self-guided WorkPlan workbook designed to support patients with cancer to return to work with fortnightly telephone support calls to discuss progress. The control group received treatment as usual and was offered the workbook at the end of their 12-month follow-up. Outcome measures We assessed aspects of feasibility including eligibility, recruitment, data collection, attrition, feasibility of the methodology, acceptability of the intervention and potential to calculate cost-effectiveness. Results The recruitment rate of eligible patients was 44%; 68 participants consented and 58 (85%) completed baseline measures. Randomisation procedures were acceptable, data collection methods (including cost-effectiveness data) were feasible and the intervention was acceptable to participants. Retention rates at 6-month and 12-month follow-up were 72% and 69%, respectively. At 6-month follow-up, 30% of the usual care group had returned to full-time or part-time work (including phased return to work) compared with 43% of the intervention group. At 12 months, the percentages were 47% (usual care) and 68% (intervention). Conclusions The findings confirm the feasibility of a definitive trial, although further consideration needs to be given to increasing the participation rates among men and black and ethnic minority patients diagnosed with cancer. Trial registration number ISRCTN56342476; Pre-results.
影响因子：
3
作者：
Pennebaker, JW;Seagal, JD
通讯作者：
Seagal, JD