A multidimensional meta-analysis of treatments for depression, panic, and generalized anxiety disorder: an empirical examination of the status of empirically supported therapies.
A multidimensional meta-analysis of treatments for depression, panic, and generalized anxiety disorder: an empirical examination of the status of empirically supported therapies.
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DOI：
10.1037/0022-006x.69.6.875
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发表时间：
2001-12
影响因子：
5.9
通讯作者：
D. Westen;Kate H. Morrison
中科院分区：
文献类型：
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作者：
D. Westen;Kate H. Morrison
作者报告了一项对1990-1998年发表的关于抑郁症、惊恐障碍和广泛性焦虑障碍（GAD）手动心理疗法疗效的高质量研究的荟萃分析，这些研究与经验支持疗法的临床效用和外部有效性有关。结果表明，相当一部分恐慌症患者得到改善并保持改善;抑郁症和广泛性焦虑症的治疗产生了令人印象深刻的短期效果：大多数抑郁症和广泛性焦虑症治疗患者没有改善，并在有临床意义的随访间隔内保持改善：许多研究中使用的筛选程序提出了关于普遍性的问题，特别是考虑到排除率和结果之间的系统性研究关系。这些数据表明，在临床试验和荟萃分析中报告一系列结局指标的重要性，这些指标提供了更全面、多维度的治疗效果及其可推广性。这些包括排除率、改善百分比、恢复百分比、随访时保持改善或恢复的百分比、随访时寻求额外治疗的百分比以及完成者和意向治疗样本的数据。
The authors report a meta-analysis of high-quality studies published from 1990-1998 on the efficacy of manualized psychotherapies for depression, panic disorder, and generalized anxiety disorder (GAD) that bear on the clinical utility and external validity of empirically supported therapies. The results suggest that a substantial proportion of patients with panic improve and remain improved; that treatments for depression and GAD produce impressive short-term effects: that most patients in treatment for depression and GAD do not improve and remain improved at clinically meaningful follow-up intervals: and that screening procedures used in many studies raise questions about generalizability, particularly in light of a systematic relation across studies between exclusion rates and outcome. The data suggest the importance of reporting, in both clinical trials and meta-analyses, a range of outcome indices that provide a more comprehensive, multidimensional portrait of treatment effects and their generalizability. These include exclusion rates, percent improved, percent recovered, percent who remained improved or recovered at follow-up, percent seeking additional treatment at follow-up, and data on both completer and intent-to-treat samples.