NASAL INTERMITTENT POSITIVE PRESSURE VENTILATION - LONG-TERM FOLLOW-UP IN PATIENTS WITH SEVERE CHRONIC RESPIRATORY INSUFFICIENCY
NASAL INTERMITTENT POSITIVE PRESSURE VENTILATION - LONG-TERM FOLLOW-UP IN PATIENTS WITH SEVERE CHRONIC RESPIRATORY INSUFFICIENCY
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DOI：
10.1378/chest.105.1.100
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发表时间：
1994-01-01
期刊：
影响因子：
9.6
通讯作者：
ROBERT, D
中科院分区：
文献类型：
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作者：
LEGER, P;BEDICAM, JM;ROBERT, D
先前的研究表明，鼻间歇正压通气（NIPPV）可以改善动脉血气值，预防肺泡通气不足引起的症状，并减少慢性呼吸衰竭患者的住院治疗。大多数研究都涉及在有限时间内随访的小样本患者。本研究回顾了276例脊柱后凸、结核后遗症、Duchenne型肌营养不良、COPD和支气管扩张患者在接受NIPPV治疗期间随访≥ 3年的5年NIPPV使用经验。比较了短期存活患者（例如，在NIPPV方案治疗的第1年或第2年期间死亡或转为气管造口术和间歇性正压通气（TIPPV）管理）和长期存活患者（例如，在NIPPV方案治疗的存活时间≥ 2年）的结局。脊柱后凸和结核后遗症患者的PaO2和PaCO2改善（p
Prior studies have shown that nasal intermittent positive pressure ventilation (NIPPV) can improve arterial blood gas values, prevent symptoms resulting from alveolar hypoventilation, and decrease hospitalization in patients with chronic respiratory failure. Most studies have involved small samples of patients followed up for a limited time. This study reviews our experience during 5 years use of NIPPV in 276 patients with kyphoscoliosis, posttuberculosis sequelae, Duchenne-type muscular dystrophy, COPD, and bronchiectasis followed up for greater than or equal to 3 years while receiving NIPPV. Outcomes were compared for patients who survived short term, eg, died or converted to management with a tracheostomy and intermittent positive ventilation (TIPPV) during year 1 or year 2 on a regimen of NIPPV and long term, eg, survived more greater than or equal to 2 years on a regimen of NIPPV. The most favorable outcome was achieved by patients with kyphoscoliosis and posttuberculous sequelae with improvement in PaO2 and PaCO2 (p