Prevalence of dry eye among the elderly
Prevalence of dry eye among the elderly
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DOI：
10.1016/s0002-9394(14)71688-5
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发表时间：
1997-12-01
影响因子：
4.2
通讯作者：
West, S
中科院分区：
文献类型：
--
作者：
Schein, OD;Munoz, B;West, S
目的：研究美国老年人干眼症的人口统计学特征并估计其患病率。方法：对2520名年龄在65岁及以上的马里兰州索尔兹伯里居民进行了一项基于人群的患病率研究。截至1993年9月。人口来源于卫生保健融资管理局的医疗保险数据库。在完成与干眼症状相关的标准化问卷调查后，2420名受试者接受了Schirmer和rose bengal测试，并对睑板腺进行了解剖评估。结果：在该人群中，14.6%（363/ 2482）有症状，定义为经常或一直报告一种或多种干眼症状；2.2%（53/2,448）有症状且Schirmer试验结果低（小于或等于5 mm）， 2%（48/2,432）有症状且rose bengal试验得分高（大于或等于5）。此外，3.5%（84/ 2425）有症状，有低Schirmer评分或高孟加拉玫瑰评分，0.7%（17/ 2420）有症状，有低Schirmer评分和高孟加拉玫瑰评分。没有发现症状或体征与年龄、性别或种族有关。虽然睑板炎的解剖特征与症状存在相关（P = 0.01），但76%（67/88）具有这些解剖特征的个体无症状；10.5%（260/ 2480）报告他们目前使用人工泪液或润滑剂。结论：干眼症的症状和体征在老年人中很常见，但在以人口为基础的美国老年人样本中与年龄、种族或性别无关。根据美国65岁至84岁的人口推算，该研究估计有430万人经常或一直有眼部刺激症状。
PURPOSE: To study the demographics and estimate the prevalence of dry eye among elderly Americans.METHODS: A population based prevalence study was performed in 2,520 residents of Salisbury, Maryland, aged 65 years and older. as of September 1993. The population was derived from the Health Care Financing Administration Medicare database. After completing a standardized questionnaire pertaining to dry eye symptoms, 2,420 subjects underwent Schirmer and rose bengal tests and anatomic assessment of the meibomian glands.RESULTS: In this population, 14.6% (363/2,482) were symptomatic, defined as reporting one or more dry eye symptoms often or all the time; 2.2% (53/2,448) were symptomatic and had a low Schirmer test result (less than or equal to 5 mm), and 2% (48/2,432) were symptomatic and had a high rose bengal test: score (greater than or equal to 5). Furthermore, 3.5% (84/2,425) were, symptomatic and had either a low Schirmer score: or a high rose bengal score, and 0.7% (17/2,420) were symptomatic and had both a low Schirmer score and a high rose bengal score. No association of symptoms or signs was seen with age, sex, or race. Although anatomic features of meibomianitis were associated with the presence of symptoms (P =.01), 76% (67/88) of the individuals with these anatomic features were asymptomatic; 10.5% (260/2,480) reported that they currently use artificial tears or lubricants.CONCLUSIONS: Symptoms and signs of dry eye are common among the elderly but were not associated with age, race, or sex in this population-based sample of elderly Americans. Extrapolating to the United States population aged 65 to 84 years, the study yields an estimate of 4.3 million who experience symptoms of ocular irritation often or all the time.