Mortality and Predictors of Death in a Cohort of Patients Presenting to an Eating Disorders Service
Mortality and Predictors of Death in a Cohort of Patients Presenting to an Eating Disorders Service
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DOI：
10.1002/eat.20715
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发表时间：
2010-07-01
影响因子：
5.5
通讯作者：
Palmer, Robert L.
中科院分区：
文献类型：
--
作者：
Button, Eric J.;Chadalavada, Bhanu;Palmer, Robert L.
目的：本研究的主要目的是调查英国成人进食障碍的死亡率。第二个目的是探讨是否有任何临床和人口统计学因素可能与increasingrisk.Method：我们进行了一项“跟踪”研究的1,892名患者的服务评估1992年至2004年。我们利用国家统计局来确定截至2007年8月记录的所有死亡人数。我们还比较了死亡的患者与匹配的控制在一些临床和人口统计学变量在最初介绍的service.Results：神经性厌食症有一个10倍的早期死亡的风险增加，但也有证据表明，在其他组的患者，包括饮食失调症的风险增加，没有另行说明。一些临床因素预测死亡风险增加，特别是非常低的体重指数和存在的酒精missions.Discussion：这项研究证实了以前的证据，神经性厌食症的死亡风险显着增加，但也表明，风险并不局限于这种饮食失调，需要更多的关注集中在更广泛的精神科合并症。(C)出版社：Wiley Periodicals，Inc.
Objective: The main aim was to investigate mortality across the spectrum of eating disorders presenting to a specialized service for adults in the UK. A secondary aim was to explore whether any clinical and demographic factors may be associated with increased risk.Method: We conducted a "tracing" study of 1,892 patients assessed by the Service between 1992 and 2004. We used the Office of National Statistics to identify all deaths recorded up to August 2007. We also compared deceased patients with matched controls in terms of a number of clinical and demographic variables at initial presentation to the service.Results: Anorexia nervosa had a ten-fold increased risk of early death, but there was also evidence of increased risk in other groups of patients, including eating disorder not otherwise specified. A number of clinical factors predicted increased mortality risk, especially very low body mass index and the presence of alcohol misuse.Discussion: The study confirms previous evidence of a markedly increased mortality risk for anorexia nervosa, but also suggests that the risk is not confined to this eating disorder and that greater attention needs to be focused on wider psychiatric comorbidity. (C) 2009 by Wiley Periodicals, Inc.